Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 12/20 | 0.38 |
| ▸ | PDE2A | O00408 | 7/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721630 | 0.87 | MTNR1A (0.47) | ALOX5SCN9APDE2A | |
| SCHEMBL3722359 | 0.83 | ALOX5 (0.42) | ALOX5SCN9APDE2ASCN10A | |
| SCHEMBL3728075 | 0.82 | SCN9A (0.35) | ALOX5SCN9ASCN10A | |
| SCHEMBL3718577 | 0.82 | PDE4B (0.48) | ALOX5SCN9APDE2A | |
| SCHEMBL3721626 | 0.80 | ACACB (0.44) | — | |
| SCHEMBL3720892 | 0.77 | AKR1C3 (0.46) | SCN9ASCN10A | |
| SCHEMBL3726204 | 0.77 | LOXL2 (0.49) | SCN9A | |
| SCHEMBL3722364 | 0.75 | LPAR1 (0.35) | SCN9A | |
| SCHEMBL3720365 | 0.74 | MAPT (0.41) | — | |
| SCHEMBL3717202 | 0.74 | ACACB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |