Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156941 | 0.85 | EGFR (0.48) | CYP2A6KMT2AMEN1KDM4EMAPT | |
| SCHEMBL27809743 | 0.78 | ESR1 (0.55) | KMT2AMEN1LMNA | |
| SCHEMBL25973229 | 0.78 | EGFR (0.47) | CYP2A6KMT2AMEN1KDM4EMAPT | |
| SCHEMBL16260860 | 0.77 | MEN1 (0.52) | CYP2A6KMT2AMEN1KDM4EMAPT | |
| SCHEMBL192166 | 0.77 | CYP2A6 (0.77) | CYP2A6KMT2AMEN1KDM4EMAPT | |
| SCHEMBL29353067 | 0.77 | CYP2A6 (0.77) | CYP2A6KMT2AMEN1KDM4EMAPT | |
| SCHEMBL17632052 | 0.77 | CYP2A6 (0.45) | CYP2A6KMT2AMEN1KDM4EMAPT | |
| SCHEMBL3719955 | 0.77 | CYP2A6 (0.45) | CYP2A6KMT2AMEN1KDM4EMAPT | |
| SCHEMBL761018 | 0.76 | ALDH1A1 (0.58) | CYP2A6KMT2AMEN1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL27157996 | 0.76 | MEN1 (0.50) | CYP2A6KMT2AMEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114544571-B | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2023-04-18 | — | — | CN | claimed |
| CN-114544571-A | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2022-05-27 | — | — | CN | claimed |
| US-8557811-B2 | Dual-color imaging method of sodium/calcium activities using two-photon fluorescent probes and preparation method of two-photon fluorescent probes | Ajou University Industry—Academic Cooperation Foundation (KR) | 2013-10-15 | — | — | US | claimed |
| US-20120035360-A1 | DUAL-COLOR IMAGING METHOD OF SODIUM/CALCIUM ACTIVITIES USING TWO-PHOTON FLUORESCENT PROBES AND PREPARATION METHOD OF TWO-PHOTON FLUORESCENT PROBES | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION | 2012-02-09 | — | — | US | claimed |
| WO-2023212818-A1 | DYES FOR MONITORING CELL STATES | Sunnybrook Research Institute (CA) | 2023-11-09 | — | — | WO | disclosed |
| CN-114544571-B | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-114544571-A | Method for constructing bioorthogonal reaction base paper device and application of bioorthogonal reaction base paper device in monoamine oxidase detection | 南京工业大学 | 2022-05-27 | — | — | CN | disclosed |
| EP-1836174-B2 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2019-10-02 | — | — | EP | disclosed |
| US-8557811-B2 | Dual-color imaging method of sodium/calcium activities using two-photon fluorescent probes and preparation method of two-photon fluorescent probes | Ajou University Industry—Academic Cooperation Foundation (KR) | 2013-10-15 | — | — | US | disclosed |
| US-8557811-B2 | Dual-color imaging method of sodium/calcium activities using two-photon fluorescent probes and preparation method of two-photon fluorescent probes | Ajou University Industry—Academic Cooperation Foundation (KR) | 2013-10-15 | — | — | US | disclosed |
| US-8557811-B2 | Dual-color imaging method of sodium/calcium activities using two-photon fluorescent probes and preparation method of two-photon fluorescent probes | Ajou University Industry—Academic Cooperation Foundation (KR) | 2013-10-15 | — | — | US | disclosed |
| EP-1836174-B1 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20080071106-A1 | Two-photon dyes for real-time imaging of lipid rafts | Korea University Industry and Academy Cooperation Foundation (KR) | 2008-03-20 | — | — | US | disclosed |
| EP-1836174-A2 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC. (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20070054916-A1 | Aryl nitrogen-containing bicyclic compounds and methods of use | AMGEN INC. | 2007-03-08 | — | — | US | disclosed |
| WO-2006039718-A2 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2006-04-13 | — | — | WO | disclosed |
| CN-1653032-A | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI CHEMICAL IND (JP) | 2005-08-10 | — | — | CN | disclosed |
| US-6867320-B2 | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-03-15 | — | — | US | disclosed |
| EP-1477472-A1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-20040044258-A1 | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035360-A1 | DUAL-COLOR IMAGING METHOD OF SODIUM/CALCIUM ACTIVITIES USING TWO-PHOTON FLUORESCENT PROBES AND PREPARATION METHOD OF TWO-PHOTON FLUORESCENT PROBES | CACNB2, CA2, ATP2A2 | CYP2A6 3082/4885KMT2A 3829/4885MEN1 1148/4885 |
| US-20040044258-A1 | Substituted phenylalkanoic acid derivatives and use thereof | PTGER1, CYSLTR1, PTGS1 | CYP2A6 318/4885KMT2A 2392/4885MEN1 4756/4885 |
| US-20070054916-A1 | Aryl nitrogen-containing bicyclic compounds and methods of use | MAP3K1, MAP3K5, MAP3K2 | CYP2A6 581/4885KMT2A 1204/4885MEN1 2987/4885 |
| US-20080071106-A1 | Two-photon dyes for real-time imaging of lipid rafts | LAMP2, FLOT1, NPC1L1 | CYP2A6 3781/4885KMT2A 3080/4885MEN1 2884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.