Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 11/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720760 | 0.81 | ALDH1A3 (0.45) | ALDH1A3P2RX3POLBKDM4E | |
| SCHEMBL3720620 | 0.81 | ADRA2A (0.41) | ADRA2AGPR65P2RX3ADRB2ADRB1 | |
| SCHEMBL13735220 | 0.78 | ALDH1A3 (0.59) | ALDH1A3P2RX3POLBGLAKDM4E | |
| SCHEMBL3717509 | 0.75 | FFAR4 (0.47) | ALDH1A3P2RX3POLBKDM4ESMN1; SMN2 | |
| SCHEMBL2723103 | 0.74 | GLA (0.57) | ADRA2AGPR65ALDH1A3P2RX3POLB | |
| SCHEMBL3726328 | 0.74 | ACACB (0.40) | ALDH1A3POLBTP53 | |
| SCHEMBL15532246 | 0.74 | TEAD4 (0.38) | POLBKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3717485 | 0.73 | KMT2A (0.49) | GLAKDM4ETP53MAPTSMN1; SMN2 | |
| SCHEMBL3720618 | 0.72 | GLA (0.43) | ADRA2AGPR65P2RX3ADRB2ADRB1 | |
| SCHEMBL25213748 | 0.70 | ALDH1A1 (0.51) | ADRA2AGPR65P2RX3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |