Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722493 | 0.79 | CRHR1 (0.31) | RBP4 | |
| SCHEMBL3727439 | 0.79 | RBP4 (0.36) | RBP4ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL766232 | 0.73 | RBP4 (0.40) | RBP4ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL631287 | 0.69 | RBP4 (0.34) | RBP4ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL766210 | 0.68 | RBP4 (0.61) | RBP4ALDH1A1MEN1KMT2ARARA | |
| SCHEMBL631288 | 0.67 | PKM (0.50) | RBP4ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1858795 | 0.61 | RARA (0.48) | RBP4MAPTRARARARBRARG | |
| SCHEMBL22240241 | 0.61 | HPGD (0.35) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL7915750 | 0.60 | ALDH1A1 (0.55) | ALDH1A1NPSR1MAPTRARARARB | |
| SCHEMBL19289494 | 0.60 | HSP90AA1 (0.37) | ALDH1A1MAPTHSP90AA1HSP90AB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010119992-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |