Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722173 | 0.95 | KDM4E (0.60) | KDM4EGAAKMT2AATMALDH1A1 | |
| SCHEMBL3724957 | 0.89 | KDM4E (0.51) | KDM4EGAAKMT2ATOP2ATSHR | |
| SCHEMBL16432203 | 0.89 | ALDH1A1 (0.67) | KDM4EGAAKMT2AALDH1A1EIF4E | |
| SCHEMBL3725674 | 0.89 | KMT2A (0.67) | KDM4EGAAKMT2AATMALDH1A1 | |
| SCHEMBL30149921 | 0.89 | KMT2A (0.67) | KDM4EGAAKMT2AATMALDH1A1 | |
| SCHEMBL71209 | 0.83 | KDM4E (0.74) | KDM4EGAAKMT2AATMALDH1A1 | |
| SCHEMBL3724952 | 0.83 | KDM4E (0.57) | KDM4EGAAKMT2AATMALDH1A1 | |
| SCHEMBL13653391 | 0.78 | KMT2A (0.68) | KDM4EGAAKMT2AATMALDH1A1 | |
| SCHEMBL16431191 | 0.78 | ALDH1A1 (0.62) | KDM4EGAAKMT2AALDH1A1EIF4E | |
| SCHEMBL29817666 | 0.78 | ALDH1A1 (0.62) | KDM4EGAAKMT2AALDH1A1EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250228880-A1 | REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2025-07-17 | — | — | US | disclosed |
| US-20170266215-A1 | REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-09-21 | — | — | US | disclosed |
| US-20100124554-A1 | REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2010-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250228880-A1 | REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS | TXN2, SQOR, LPO | KDM4E 3013/4885GAA 968/4885KMT2A 3971/4885 |
| US-20100124554-A1 | REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS | TXN2, SQOR, LPO | KDM4E 3013/4885GAA 968/4885KMT2A 3971/4885 |
| US-20170266215-A1 | REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS | TXN2, SQOR, LPO | KDM4E 3013/4885GAA 968/4885KMT2A 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.