Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722382 | 0.87 | ALOX5 (0.35) | KCNH3MAP4K4SCN9ATDP1ALOX5 | |
| SCHEMBL3719940 | 0.83 | ACACA (0.48) | HCRTR1TDP1 | |
| SCHEMBL3722736 | 0.81 | TAAR1 (0.36) | KCNH3MAP4K4SCN9ASCN7AKCNH2 | |
| SCHEMBL3724455 | 0.81 | KCNH3 (0.37) | KCNH3MAP4K4SCN9A | |
| SCHEMBL3719854 | 0.80 | FGFR2 (0.37) | KCNH3MAP4K4SCN9ATDP1ALOX5 | |
| SCHEMBL3723898 | 0.80 | PDE4B (0.50) | — | |
| SCHEMBL3722861 | 0.80 | — | — | |
| SCHEMBL3723899 | 0.79 | KCNH3 (0.36) | KCNH3MAP4K4SCN9ASCN7AKCNH2 | |
| SCHEMBL3721952 | 0.78 | SCN9A (0.37) | MAP4K4SCN9A | |
| SCHEMBL3720364 | 0.76 | NCF1 (0.38) | MAP4K4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |