Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722382 | 0.83 | ALOX5 (0.35) | SCN9ASCN10AMAP4K4 | |
| SCHEMBL3722765 | 0.83 | ACACB (0.45) | SCN9A | |
| SCHEMBL3720074 | 0.82 | JAK2 (0.36) | SCN9AMAP4K4HCAR3 | |
| SCHEMBL3721953 | 0.81 | SCN9A (0.36) | SCN9ASCN10AMAP4K4 | |
| SCHEMBL3720127 | 0.80 | PDE4B (0.49) | SCN9ASCN10AHCAR3 | |
| SCHEMBL3720129 | 0.79 | ACACB (0.37) | SCN9AHCAR3 | |
| SCHEMBL3722734 | 0.78 | KCNH3 (0.38) | SCN9AMAP4K4 | |
| SCHEMBL3720364 | 0.78 | NCF1 (0.38) | MAP4K4 | |
| SCHEMBL3804254 | 0.76 | TLR8 (0.39) | SCN9ASCN10AMAP4K4 | |
| SCHEMBL3720908 | 0.75 | ACACB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |