Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614077 | 0.85 | ALDH1A1 (0.37) | CA2TRPM8L3MBTL1KDM4ELMNA | |
| SCHEMBL8705267 | 0.70 | GRIN2C (0.40) | TRPM8 | |
| SCHEMBL3715260 | 0.70 | ALDH1A1 (0.52) | GPR35CA2L3MBTL1KDM4E | |
| SCHEMBL29199762 | 0.68 | IKBKB (0.46) | TRPM8KDM4ELMNA | |
| SCHEMBL319190 | 0.68 | GPR35 (0.57) | GPR35PTPN1KDM4E | |
| SCHEMBL5121549 | 0.67 | GRM6 (0.49) | TRPM8KDM4ELMNA | |
| SCHEMBL3715482 | 0.67 | PTPN5 (0.38) | GPR35CA2L3MBTL1PTPN1 | |
| SCHEMBL26626874 | 0.65 | GPR35 (0.48) | GPR35PTPN1KDM4E | |
| SCHEMBL20894452 | 0.65 | GPR35 (0.48) | GPR35PTPN1KDM4E | |
| SCHEMBL14910293 | 0.65 | ALDH1A1 (0.54) | CA2L3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101302-A1 | THIENOPYRIMIDINE AS CDC7 KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-10 | — | — | WO | disclosed |