SCHEMBL372307

SCHEMBL372307

O=C(O)c1cccc(Cl)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.65
ALDH1A1 P00352 6/20 0.64
KDM4E B2RXH2 4/20 0.61
HSD17B10 Q99714 3/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
RXFP1 Q9HBX9 1/20 0.61
HPGD P15428 3/20 0.57
ALB P02768 1/20 0.57
MMP2 P08253 1/20 0.57
HNF4A P41235 1/20 0.53
AKR1C2 P52895 4/20 0.53
AKR1C1 Q04828 4/20 0.53
AKR1C4 P17516 1/20 0.52
AKR1C3 P42330 1/20 0.52
DPP4 P27487 1/20 0.50
ALOX15 P16050 1/20 0.50
MAPT P10636 1/20 0.50
PKM P14618 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29499766 1.00 TSHR (0.65) TSHRALDH1A1KDM4EHSD17B10MEN1
SCHEMBL431965 0.98 TSHR (0.63) TSHRALDH1A1KDM4EHSD17B10MEN1
Ammonia Solution, Strong SCHEMBL28934927 0.98 TSHR (0.63) TSHRALDH1A1KDM4EHSD17B10MEN1
SCHEMBL425111 0.98 TSHR (0.63) TSHRALDH1A1KDM4EHSD17B10MEN1
SCHEMBL10779360 0.98 TSHR (0.63) TSHRALDH1A1KDM4EHSD17B10MEN1
SCHEMBL10779351 0.98 TSHR (0.63) TSHRALDH1A1KDM4EHSD17B10MEN1
Bicarbonate SCHEMBL28208484 0.92 TSHR (0.57) TSHRALDH1A1KDM4EHSD17B10MEN1
Salicylic Acid SCHEMBL28162812 0.90 ALDH1A1 (0.67) TSHRALDH1A1KDM4EHSD17B10MEN1
SCHEMBL28101443 0.83 TSHR (0.47) TSHRALDH1A1KDM4EHSD17B10MEN1
SCHEMBL110532 0.83 ALDH1A1 (0.70) TSHRALDH1A1KDM4EHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 895 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US claimed
EP-4352449-B1 PROJECTILE PAYLOAD FOR TRAINING AMMUNITION WITH MULTI-SPECTRAL OUTPUT CYALUME TECH INC (US) 2025-05-07 EP claimed
CN-222724310-U 5-Chlorosalicylic acid synthesis system 内蒙古百灵科技有限公司 2025-04-08 CN claimed
EP-4501896-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND Kao Corporation (JP) 2025-02-05 EP claimed
CN-119280450-A Medical fabric dressing with long-acting disinfection and sterilization functions and preparation method thereof 孙国明 2025-01-10 CN claimed
CN-118973990-A Process for producing cyclic diketone compound 花王株式会社 2024-11-15 CN claimed
CN-118844836-A Long-acting disinfection and sterilization wet (towel) paper 孙国明 2024-10-29 CN claimed
CN-118844448-A Preparation method of long-acting antibacterial liquid 孙国明 2024-10-29 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
US-6294186-B1 Antimicrobial compositions comprising a benzoic acid analog and a metal salt PROCTER & GAMBLE COMPANY, THR 2001-09-25 US claimed
EP-1112347-A1 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS Northwest Plant Breeding Co. (US) 2001-07-04 EP claimed
WO-2001014518-A2 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING CO. (US) 2001-03-01 WO claimed
EP-1018927-A1 LIGHTING ELEMENT FOR VISUAL OR PHOTOGRAPHIC MEDICAL EXAMINATION Laboratoires Piette International S.A. (BE) 2000-07-19 EP claimed
WO-2000014202-A1 METHODS FOR GENERATING DOUBLED HAPLOID PLANTS NORTHWEST PLANT BREEDING COMPANY (US) 2000-03-16 WO claimed
WO-1999016342-A1 LIGHTING ELEMENT FOR VISUAL OR PHOTOGRAPHIC MEDICAL EXAMINATION LABORATOIRES PIETTE INTERNATIONAL S.A. (BE) 1999-04-08 WO claimed
US-5194666-A Intermediates for chemiluminescent agents, chlorination, esterification AMERICAN CYANAMID COMPANY (US) 1993-03-16 US claimed
EP-0147947-A1 Insecticidal composition CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1985-07-10 EP claimed
EP-0031561-B1 A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT MERCK & CO. INC. (US) 1985-04-10 EP claimed
US-4308395-A Processes for preparing 3,5,6-trichlorosalicylic acid and esters thereof AMERICAN CYANAMID COMPANY (US) 1981-12-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND HSD17B7, HSD17B12, BCKDK TSHR 4605/4885ALDH1A1 699/4885KDM4E 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.