Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1220435 | 0.87 | MAPT (0.41) | NPC1RAB9ACYP1A2 | |
| SCHEMBL3724820 | 0.85 | LMNA (0.41) | KCNH2NPC1RAB9ASCN9A | |
| SCHEMBL1221118 | 0.85 | CYP1A2 (0.43) | GPR3S1PR1NPC1RAB9ASCN5A | |
| SCHEMBL3728740 | 0.83 | L3MBTL1 (0.36) | KCNH2NPC1RAB9ASCN9ACYP1A2 | |
| SCHEMBL3718958 | 0.83 | ACACB (0.39) | KCNH2NPC1RAB9A | |
| SCHEMBL3717489 | 0.82 | DRD2 (0.44) | NPC1RAB9A | |
| SCHEMBL542216 | 0.82 | KCNH2 (0.42) | KCNH2NPC1RAB9ACACNA1G | |
| SCHEMBL3717968 | 0.82 | MAOB (0.41) | KCNH2NPC1RAB9A | |
| SCHEMBL1220445 | 0.81 | KCNH2 (0.51) | KCNH2CACNA1G | |
| SCHEMBL3716786 | 0.81 | PDK2 (0.40) | KCNH2NPC1RAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081149-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLAXOSMITHKLINE LLC (US) | 2010-07-15 | — | — | WO | disclosed |