Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724820 | 0.84 | LMNA (0.41) | PDK2KCNH2NPC1RAB9ASCN9A | |
| SCHEMBL3718958 | 0.82 | ACACB (0.39) | PDK2KCNH2NPC1RAB9A | |
| SCHEMBL3728740 | 0.82 | L3MBTL1 (0.36) | KCNH2NPC1RAB9ASCN9A | |
| SCHEMBL3723404 | 0.81 | GPR3 (0.37) | KCNH2NPC1RAB9ASCN9A | |
| SCHEMBL1220435 | 0.81 | MAPT (0.41) | NPC1RAB9A | |
| SCHEMBL3717968 | 0.81 | MAOB (0.41) | KCNH2NPC1RAB9A | |
| SCHEMBL542216 | 0.77 | KCNH2 (0.42) | CNR2TRPA1KCNH2NPC1RAB9A | |
| SCHEMBL1220445 | 0.76 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL3721640 | 0.74 | KCNH2 (0.39) | KCNH2NPC1RAB9A | |
| SCHEMBL3721862 | 0.74 | CACNA1G (0.42) | KCNH2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081149-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLAXOSMITHKLINE LLC (US) | 2010-07-15 | — | — | WO | disclosed |