SCHEMBL3724948

SCHEMBL3724948

O=C(O)c1c(O)ccc2nc3cccc(O)c3nc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.55
ALDH1A1 P00352 4/20 0.55
KMT2A Q03164 2/20 0.55
RAB9A P51151 2/20 0.55
MAPT P10636 2/20 0.55
GAA P10253 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NQO2 P16083 1/20 0.47
KDM4E B2RXH2 2/20 0.44
EIF4E P06730 2/20 0.41
EIF4EBP1 Q13541 2/20 0.41
CYP1A2 P05177 1/20 0.39
LMNA P02545 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3721381 0.95 ACHE (0.62) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL3735695 0.86 ALDH1A1 (0.56) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL29381124 0.86 ALDH1A1 (0.56) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL5886263 0.84 CA12 (0.46) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL17866709 0.83 KMT2A (0.47) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL16431388 0.83 ALDH1A1 (0.50) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL16431227 0.82 ALDH1A1 (0.65) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL13439504 0.80 ACHE (0.85) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL3724658 0.79 ALDH1A1 (0.71) ACHEALDH1A1KMT2ARAB9AMAPT
SCHEMBL30468172 0.79 ALDH1A1 (0.71) ACHEALDH1A1KMT2ARAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228880-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2025-07-17 US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20170266215-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2017-09-21 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed
US-20100124554-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS CALIFORNIA INSTITUTE OF TECHNOLOGY 2010-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228880-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS TXN2, SQOR, LPO ACHE 574/4885ALDH1A1 720/4885KMT2A 3971/4885
US-20100124554-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS TXN2, SQOR, LPO ACHE 574/4885ALDH1A1 720/4885KMT2A 3971/4885
US-20170266215-A1 REDOX-ACTIVE COMPOUNDS AND RELATED COMPOUNDS, COMPOSITIONS, METHODS AND SYSTEMS TXN2, SQOR, LPO ACHE 574/4885ALDH1A1 720/4885KMT2A 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.