Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676164 | 0.91 | HSD11B1 (0.44) | HSD11B1TNKSPARP1PARP2CHRM4 | |
| SCHEMBL4739224 | 0.88 | KDM4E (0.48) | OPRM1OPRK1OPRL1BCHEACHE | |
| SCHEMBL1836672 | 0.86 | OPRM1 (0.44) | HSD11B1TNKSPARP1PARP2OPRM1 | |
| SCHEMBL3403017 | 0.84 | OPRM1 (0.50) | OPRM1OPRK1OPRL1BCHEACHE | |
| SCHEMBL1835272 | 0.84 | OPRM1 (0.50) | OPRM1OPRK1OPRL1BCHEACHE | |
| SCHEMBL3726211 | 0.83 | FPR2 (0.35) | TNKSPARP1PARP2OPRM1OPRK1 | |
| SCHEMBL3398856 | 0.80 | PLD2 (0.46) | HSD11B1OPRM1OPRK1OPRL1BCHE | |
| SCHEMBL1837581 | 0.80 | OPRK1 (0.44) | HSD11B1OPRM1OPRK1OPRL1BCHE | |
| SCHEMBL1838176 | 0.80 | OPRK1 (0.50) | HSD11B1OPRM1OPRK1OPRL1BCHE | |
| SCHEMBL3399651 | 0.80 | OPRM1 (0.52) | OPRM1OPRK1OPRL1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | claimed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | claimed |