Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728857 | 0.90 | STK39 (0.41) | MTNR1AMTNR1BHTR2CHTR2B | |
| SCHEMBL3720296 | 0.86 | SCN9A (0.45) | SMN1; SMN2 | |
| SCHEMBL3720102 | 0.82 | PDE10A (0.47) | PDE10A | |
| SCHEMBL3717395 | 0.79 | HDAC1 (0.42) | PDE10A | |
| SCHEMBL3717394 | 0.79 | HDAC8 (0.44) | — | |
| SCHEMBL3726420 | 0.77 | ACACB (0.47) | — | |
| SCHEMBL3722351 | 0.77 | SMN1; SMN2 (0.54) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL3720624 | 0.76 | ALDH1A1 (0.49) | MTNR1AMTNR1BHTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL3724749 | 0.75 | ACACB (0.45) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL3719665 | 0.74 | ACACB (0.54) | MTNR1AMTNR1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |