Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13191711 | 0.91 | P2RX7 (0.37) | P2RX7EPHX2PDE4BCNR2TP53 | |
| SCHEMBL3722075 | 0.91 | P2RX7 (0.37) | P2RX7EPHX2BDKRB1PDE4BCNR2 | |
| SCHEMBL13191712 | 0.89 | BDKRB1 (0.38) | P2RX7EPHX2BDKRB1PDE4BCNR2 | |
| SCHEMBL3722055 | 0.89 | P2RX7 (0.35) | P2RX7EPHX2PDE4BCNR2MAPK8 | |
| SCHEMBL3725868 | 0.88 | MEN1 (0.41) | P2RX7EPHX2BDKRB1PDE4BCNR2 | |
| SCHEMBL3721990 | 0.87 | BDKRB1 (0.37) | P2RX7EPHX2CNR1BDKRB1PDE4B | |
| SCHEMBL3722006 | 0.86 | P2RX7 (0.40) | P2RX7EPHX2PDE4BCNR2MAPK8 | |
| SCHEMBL13165640 | 0.82 | L3MBTL1 (0.41) | P2RX7EPHX2 | |
| SCHEMBL3725821 | 0.81 | P2RX7 (0.40) | P2RX7EPHX2BDKRB1MAPK8MAPK10 | |
| SCHEMBL13165638 | 0.80 | EPHX2 (0.40) | P2RX7EPHX2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |