Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122099 | 0.85 | PLIN1 (0.41) | TDP1 | |
| SCHEMBL3728876 | 0.85 | PLIN1 (0.41) | TDP1 | |
| SCHEMBL29424499 | 0.85 | PLIN1 (0.41) | TDP1 | |
| Dimethyl Sulfone SCHEMBL19032723 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL8806093 | 0.79 | ALDH1A1 (0.37) | TDP1 | |
| Phosmet SCHEMBL1070968 | 0.75 | ALDH1A1 (0.63) | TDP1 | |
| SCHEMBL8806099 | 0.74 | ALDH1A1 (0.39) | TDP1 | |
| SCHEMBL11444062 | 0.71 | POLB (0.49) | ELANETDP1 | |
| SCHEMBL2815496 | 0.70 | POLB (0.44) | ELANETDP1 | |
| SCHEMBL11688456 | 0.69 | ALDH1A1 (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617525-B2 | Phosphotriesterase enzymes, methods and compositions related thereto | NEW YORK UNIVERSITY (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160083702-A1 | NOVEL PHOSPHOTRIESTERASE ENZYMES, METHODS AND COMPOSITIONS RELATED THERETO | NEW YORK UNIVERSITY | 2016-03-24 | — | — | US | disclosed |
| EP-0214507-B1 | OUTDOOR FILMS STABILIZED AGAINST CHEMICAL ATTACK | AMERICAN CYANAMID COMPANY (US) | 1992-01-15 | — | — | EP | disclosed |