SCHEMBL3729335

SCHEMBL3729335

O=C(O)COCCOCCCl

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
TSHR P16473 4/20 0.36
CTH P32929 1/20 0.36
CBS P35520 1/20 0.36
THPO P40225 1/20 0.36
THRB P10828 1/20 0.35
EPHX2 P34913 1/20 0.31
CYP2C19 P33261 1/20 0.30
ALDH1A1 P00352 2/20 0.30
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7262941 1.00 HSD17B10 (0.38) HSD17B10BLMPMP22TSHRCTH
SCHEMBL18173867 1.00 HSD17B10 (0.38) HSD17B10BLMPMP22TSHRCTH
SCHEMBL1438928 0.95
Hydrochloric Acid SCHEMBL4912304 0.92
SCHEMBL81956 0.87 HSD17B10 (0.46) HSD17B10BLMPMP22TSHRCTH
SCHEMBL6666413 0.87 HSD17B10 (0.46) HSD17B10BLMPMP22TSHRCTH
SCHEMBL14950228 0.87 HSD17B10 (0.46) HSD17B10BLMPMP22TSHRCTH
SCHEMBL6664456 0.87 HSD17B10 (0.46) HSD17B10BLMPMP22TSHRCTH
SCHEMBL20534906 0.87 HSD17B10 (0.46) HSD17B10BLMPMP22TSHRCTH
SCHEMBL25495618 0.87 HSD17B10 (0.46) HSD17B10BLMPMP22TSHRCTH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169618-B2 Magnetic particles and methods of producing coated magnetic particles SKOLD TECHNOLOGY (US) 2007-01-30 US claimed
US-20020000398-A1 Magnetic particles and methods of producing coated magnetic particles SKOLD TECHNOLOGY 2002-01-03 US claimed
WO-2025137541-A1 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2025-06-26 WO disclosed
US-12239639-B2 Cytotoxic actin-targeting compounds QUEEN'S UNIVERSITY AT KINGSTON (CA) 2025-03-04 US disclosed
CN-114174299-B Degradation of Bruton's Tyrosine Kinase (BTK) by conjugation of BTK inhibitors to E3 ligase ligand and methods of use 百济神州有限公司 2024-10-25 CN disclosed
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H BIOTECH INC. (KR) 2023-10-12 US disclosed
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H BIOTECH INC. (KR) 2023-10-12 US disclosed
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H BIOTECH INC. (KR) 2023-10-12 US disclosed
CN-116490184-A Compounds for inhibiting EGFR mutant cancers and pharmaceutical uses thereof J2H生物科技有限公司 2023-07-25 CN disclosed
EP-4212522-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H Biotech Inc. (KR) 2023-07-19 EP disclosed
EP-4212522-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF J2H Biotech Inc. (KR) 2023-07-19 EP disclosed
US-20050192430-A1 Linker arms for nanocrystals and compounds thereof ROSENTHAL SANDRA J (US) 2005-09-01 US disclosed
WO-2005010481-A2 PREPARATION AND USE OF GOLD GLYCONANOPARTICLES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-02-03 WO disclosed
US-20030138432-A1 Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs DRUG INNOVATION & DESIGN, INC. 2003-07-24 US disclosed
US-20030129590-A1 Linker arms for nanocrystals and compounds thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-07-10 US disclosed
EP-1255567-A1 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES Drug Innovation & Design, Inc. (US) 2002-11-13 EP disclosed
WO-2001090716-A2 LINKER ARMS FOR NANOCRYSTALS AND COMPOUNDS THEREOF VANDERBILT UNIVERSITY (US) 2001-11-29 WO disclosed
WO-2001036003-A2 SELECTIVE CELLULAR TARGETING: MULTIFUNCTIONAL DELIVERY VEHICLES DRUG INNOVATION & DESIGN, INC. (US) 2001-05-25 WO disclosed
EP-0048705-B1 2-(4-(DIPHENYLMETHYLENE)-1-PIPERIDINYL)-ACETIC ACIDS AND THEIR AMIDES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM U C B, S.A. (BE) 1984-07-11 EP disclosed
US-4443460-A ANTIALLERGENS, ANTIHISTAMINES, ANTISPASMODICS, BRONCHODILATORS UCB, SOCIETE ANONYME (BE) 1984-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030129590-A1 Linker arms for nanocrystals and compounds thereof SCO2, NCL, NCAPH HSD17B10 2214/4885BLM 3756/4885PMP22 2543/4885
US-12239639-B2 Cytotoxic actin-targeting compounds ACTB, ACTR2, MYC HSD17B10 2938/4885BLM 3046/4885PMP22 4509/4885
US-20230322723-A1 COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF EGFR, KRAS, ERBB2 HSD17B10 2789/4885BLM 3073/4885PMP22 4563/4885
US-20030138432-A1 Selective cellular targeting: multifunctional delivery vehicles, multifunctional prodrugs, use as antineoplastic drugs PAICS, ABCB1, ABCG2 HSD17B10 2241/4885BLM 4257/4885PMP22 4128/4885
US-20050192430-A1 Linker arms for nanocrystals and compounds thereof NCL, CHN2, SCO2 HSD17B10 3601/4885BLM 4194/4885PMP22 4240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.