SCHEMBL373266

SCHEMBL373266

N[C@]1(C(=O)O)O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ IDUA P35475 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20888665 0.77 IDUA (0.33) IDUA
SCHEMBL22096149 0.77 IDUA (0.33) IDUA
SCHEMBL20888684 0.76 PYGB (0.44) —
SCHEMBL14432962 0.76 PYGB (0.44) —
SCHEMBL20888681 0.76 PYGB (0.44) —
SCHEMBL18820182 0.76 PYGB (0.44) —
SCHEMBL18805897 0.76 PYGB (0.44) —
SCHEMBL18819607 0.74 PYGB (0.39) IDUA
SCHEMBL18819604 0.74 PYGB (0.39) IDUA
SCHEMBL17256226 0.70 IDUA (0.38) IDUA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871744-B2 Compounds and methods for selectively targeting tumor-associated mucins B & G Partyers, LLC (US) 2014-10-28 — — US disclosed
US-8778892-B2 Compounds and methods for treatment of solid tumors B & G PARTNERS, LLC (US) 2014-07-15 — — US disclosed
US-20120295284-A1 Fluorecent Saccharide Conjugates B&G PARTNERS, LLC 2012-11-22 — — US disclosed
US-20120022016-A1 Compounds and methods for selectively targeting tumor-associated mucins B&G PARTNERS, LLC 2012-01-26 — — US disclosed
EP-2409708-A1 Compounds and methods for selectively targeting tumor-associated mucins B & G Partners, LLC (US) 2012-01-25 — — EP disclosed
US-20100240878-A1 Fluorescent saccharide conjugates B&G PARTNERS, LLC 2010-09-23 — — US disclosed
US-20090239820-A1 Compounds and methods for treatment of solid tumors BARBEAU DONALD L 2009-09-24 — — US disclosed
US-5952313-A COMPOSITION FOR ANTAGONIZING GRAM NEGATIVE BACTERIAL ENDOTOXIC ACTIVITY, COMPRISING A PHARMACEUTICALLY ACCEPTABLE CARRIER AND AN ANTAGONIZING AMOUNT OF A LIPOPOLYSACCHARIDE FROM A RHIZOBIUM ETLI; TREATMENT OF SEPTIC SHOCK OR TOXIC SHOCK UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1999-09-14 — — US disclosed
EP-0824538-A1 SACCHAROPEPTIDES AND DERIVATIVES THEREOF GLYCOMED INCORPORATED (US) 1998-02-25 — — EP disclosed
US-5648343-A ADMINISTERING A LIPID THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) 1997-07-15 — — US disclosed
WO-1996035700-A9 SACCHAROPEPTIDES AND DERIVATIVES THEREOF — 1997-02-13 — — WO disclosed
EP-0748327-A1 STRUCTURE OF A NOVEL LIPID A AND METHODS UTILIZING SAME THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1996-12-18 — — EP disclosed
WO-1996035700-A1 SACCHAROPEPTIDES AND DERIVATIVES THEREOF GLYCOMED INCORPORATED (US) 1996-11-14 — — WO disclosed
WO-1995023156-A1 STRUCTURE OF A NOVEL LIPID A AND METHODS UTILIZING SAME UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1995-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240878-A1 Fluorescent saccharide conjugates CD44, FUT6, SIGLEC7 IDUA 547/4885
US-20120022016-A1 Compounds and methods for selectively targeting tumor-associated mucins MUC1, NEU4, ALK IDUA 108/4885
US-20090239820-A1 Compounds and methods for treatment of solid tumors VHL, HCAR1, HCAR2 IDUA 158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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