Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | HTR1D | P28221 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4548474 | 0.90 | DRD2 (0.35) | ALDH1A1DRD2DRD3HTR1DDRD4 | |
| SCHEMBL10014981 | 0.81 | DRD2 (0.40) | ALDH1A1KMT2ADRD2DRD3HTR1D | |
| SCHEMBL4548487 | 0.79 | DRD2 (0.32) | DRD2DRD3HTR1DDRD4HTR5A | |
| SCHEMBL3598479 | 0.74 | CXCR2 (0.32) | DRD2DRD3HTR1D | |
| SCHEMBL3589428 | 0.74 | CXCR2 (0.32) | DRD2DRD3HTR1D | |
| SCHEMBL502662 | 0.74 | SLC6A3 (0.37) | — | |
| SCHEMBL4548472 | 0.74 | SLC6A3 (0.39) | ALDH1A1MAPT | |
| SCHEMBL13920731 | 0.74 | HCAR2 (0.36) | DRD2DRD3HTR1DHCAR2 | |
| SCHEMBL13933933 | 0.74 | ALDH1A1 (0.33) | ALDH1A1KMT2ADRD2DRD3HTR1D | |
| SCHEMBL17532276 | 0.73 | DRD2 (0.35) | DRD2DRD3HTR1DDRD4HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079840-A9 | BENZOCHROMENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-07-12 | — | — | WO | disclosed |
| EP-1963298-B1 | Benzochromene derivatives | MERCK PATENT GMBH (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-7824745-B2 | Benzochromene derivatives | MERCK PATENT GMBH (DE) | 2010-11-02 | — | — | US | disclosed |
| US-7824745-B2 | Benzochromene derivatives | MERCK PATENT GMBH (DE) | 2010-11-02 | — | — | US | disclosed |
| US-7824745-B2 | Benzochromene derivatives | MERCK PATENT GMBH (DE) | 2010-11-02 | — | — | US | disclosed |
| US-20090023802-A1 | Benzochromene Derivatives | MERCK PATENT GMBH (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20090023802-A1 | Benzochromene Derivatives | MERCK PATENT GMBH (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20090023802-A1 | Benzochromene Derivatives | MERCK PATENT GMBH (DE) | 2009-01-22 | — | — | US | disclosed |
| WO-2007079840-A2 | BENZOCHROMENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023802-A1 | Benzochromene Derivatives | SBDS, CRY1, DDT | ALDH1A1 676/4885KMT2A 4195/4885DRD2 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.