Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626511 | 0.87 | L3MBTL1 (0.48) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1SYK | |
| SCHEMBL3737611 | 0.84 | HDAC3 (0.46) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1SYK | |
| SCHEMBL3742299 | 0.84 | EPHX2 (0.43) | L3MBTL1ALDH1A1HTTMEN1MAPT | |
| SCHEMBL31170532 | 0.83 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1SYK | |
| SCHEMBL27003934 | 0.81 | HDAC3 (0.45) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1SYK | |
| SCHEMBL29077734 | 0.79 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1SYK | |
| SCHEMBL7332893 | 0.79 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1MAPK1SYKMEN1 | |
| SCHEMBL28956076 | 0.79 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1SYK | |
| SCHEMBL20089220 | 0.78 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2ALDH1A1MAPK1SYK | |
| SCHEMBL9787659 | 0.77 | POLB (0.45) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710000-B2 | Insulin derivative | NOVO NORDISK A/S (DK) | 2014-04-29 | — | — | US | disclosed |
| US-20100279931-A1 | Insulin Derivative | NOVO NORDISK A/S | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279931-A1 | Insulin Derivative | IAPP, INSR, GPR119 | L3MBTL1 4749/4885SMN1; SMN2 2683/4885ALDH1A1 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.