Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3742291 | 0.88 | EPHX2 (0.46) | EPHX2SIRT2ALDH1A1HPGDMEN1 | |
| SCHEMBL3737616 | 0.84 | L3MBTL1 (0.43) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL17599919 | 0.80 | CYP3A4 (0.59) | EPHX2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL23777326 | 0.78 | TPSAB1 (0.56) | EPHX2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3052852 | 0.78 | HTT (0.61) | EPHX2MAPTL3MBTL1CYP3A4TPSAB1 | |
| SCHEMBL9667908 | 0.78 | HTT (0.61) | EPHX2MAPTL3MBTL1CYP3A4TPSAB1 | |
| SCHEMBL2417332 | 0.78 | TPSAB1 (0.56) | EPHX2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL25787604 | 0.78 | HTT (0.61) | EPHX2MAPTL3MBTL1CYP3A4TPSAB1 | |
| SCHEMBL28379687 | 0.77 | LMNA (0.49) | EPHX2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3742296 | 0.77 | EPHX2 (0.47) | EPHX2ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710000-B2 | Insulin derivative | NOVO NORDISK A/S (DK) | 2014-04-29 | — | — | US | disclosed |
| US-20100279931-A1 | Insulin Derivative | NOVO NORDISK A/S | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279931-A1 | Insulin Derivative | IAPP, INSR, GPR119 | EPHX2 3794/4885SIRT2 880/4885ALDH1A1 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.