SCHEMBL373958

SCHEMBL373958

C=CCC(=CP(=O)(O)O)CC=C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 3/20 0.33
FNTB P49356 3/20 0.33
PGGT1B P53609 1/20 0.30
LPAR2 Q9HBW0 1/20 0.30
LPAR3 Q9UBY5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL4365459 0.70 ALOX15 (0.43) LPAR2LPAR3
SCHEMBL2720597 0.70 FNTA (0.38) FNTAFNTBPGGT1B
SCHEMBL11471773 0.67 LPAR2 (0.32) LPAR2LPAR3
SCHEMBL371404 0.67 CA2 (0.32)
Phosphoric Acid SCHEMBL27640814 0.65
Phosphoric Acid SCHEMBL9573624 0.65 ALDH1A1 (0.38)
SCHEMBL10712520 0.65
SCHEMBL3470139 0.65
SCHEMBL635119 0.65
SCHEMBL11883585 0.64 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120116074-A1 METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF CULLEN THOMAS GERARD (US) 2012-05-10 US claimed
EP-2408790-A1 METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF Wyeth LLC (US) 2012-01-25 EP claimed
WO-2010108063-A1 METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF WYETH LLC (US) 2010-09-23 WO claimed
CN-108026223-B Use of sulfur-or phosphorus-containing polymers as processing aids in polyvinyl chloride polymer compositions 辛色姆(英国)有限公司 2021-03-09 CN disclosed
US-20140322786-A1 POLYMER MODIFIED SUBSTRATES, THEIR PREPARATION AND USES THEREOF APCETH GMBH & CO KG (DE) 2014-10-30 US disclosed
EP-2780122-A1 POLYMER MODIFIED SUBSTRATES, THEIR PREPARATION AND USES THEREOF Apceth GmbH & Co. KG (DE) 2014-09-24 EP disclosed
WO-2013072309-A1 POLYMER MODIFIED SUBSTRATES, THEIR PREPARATION AND USES THEREOF F. HOFFMANN-LA ROCHE AG (CH) 2013-05-23 WO disclosed
US-20120116074-A1 METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF CULLEN THOMAS GERARD (US) 2012-05-10 US disclosed
EP-2408790-A1 METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF Wyeth LLC (US) 2012-01-25 EP disclosed
WO-2010108063-A1 METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF WYETH LLC (US) 2010-09-23 WO disclosed
US-4014839-A BIS(HYDROCARBYL)VINYL PHOSPHONATES STAUFFER CHEMICAL COMPANY (US) 1977-03-29 US disclosed
US-4014837-A BIS(HYDROCARBYL)VINYL PHOSPHONATES STAUFFER CHEMICAL COMPANY (US) 1977-03-29 US disclosed
US-4014836-A BIS(HYDROCARBYL)VINYL PHOSPHONATES STAUFFER CHEMICAL COMPANY (US) 1977-03-29 US disclosed
US-4014838-A BIS(HYDROCARBYL)VINYL PHOSPHONATES STAUFFER CHEMICAL COMPANY (US) 1977-03-29 US disclosed
US-3948842-A Fire retardant polymeric additives of vinylidene halides with bis(hydrocarbyl) vinyl phosphonates and C1 -C20 alkylesters of acrylic and methacrylic acids STAUFFER CHEMICAL COMPANY (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120116074-A1 METHODS FOR THE PREPARATION OF [2-(8,9-DIOXO-2,6-DIAZABICYCLO[5.2.0]NON-1(7)-EN-2-YL)ETHYL]PHOSPHONIC ACID AND PRECURSORS THEREOF DERA, ENO1, PPIP5K2 FNTA 983/4885FNTB 1421/4885PGGT1B 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.