Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432109 | 0.83 | KMT2A (0.41) | ALDH1A1KMT2AGAANPSR1NPC1 | |
| SCHEMBL5066069 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1KMT2AGAACXCL8NPSR1 | |
| SCHEMBL5740669 | 0.81 | CES2 (0.42) | KMT2ALMNAHPGDCES2CES1 | |
| SCHEMBL27602026 | 0.79 | KDM4E (0.44) | ALDH1A1KMT2AGAACXCL8PARP10 | |
| SCHEMBL247351 | 0.79 | PTGS2 (0.57) | ALDH1A1KMT2AGAACXCL8PARP10 | |
| Ammonia Solution, Strong SCHEMBL4479016 | 0.78 | PTGS2 (0.55) | ALDH1A1KMT2AGAACXCL8PARP10 | |
| SCHEMBL1957403 | 0.78 | PTPN1 (0.44) | ALDH1A1KMT2ANPSR1NPC1SMN1; SMN2 | |
| SCHEMBL22833915 | 0.78 | CA1 (0.54) | ALDH1A1KMT2ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL27623412 | 0.78 | TSHR (0.50) | ALDH1A1KMT2AGAANPSR1NPC1 | |
| SCHEMBL7158597 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GAASMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
| CN-1285561-C | Alpha, beta-unsaturated ketone compound and its prepn process and GST-Pi inhibiting activity | UNIV SHANDONG (CN) | 2006-11-22 | — | — | CN | disclosed |
| CN-1706789-A | Alpha, beta-unsaturated ketone compound and its prepn process and GST-Pi inhibiting activity | UNIV SHANDONG (CN) | 2005-12-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | ALDH1A1 458/4885KMT2A 3443/4885GAA 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.