Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20609994 | 0.80 | TDO2 (0.33) | TDO2KDM4EMEN1KMT2A | |
| SCHEMBL29906286 | 0.80 | TDO2 (0.33) | TDO2KDM4EMEN1KMT2A | |
| SCHEMBL15917838 | 0.79 | — | — | |
| SCHEMBL25865218 | 0.79 | TDO2 (0.33) | TDO2 | |
| SCHEMBL1455223 | 0.77 | NPC1 (0.36) | NPC1LMNATP53RAB9ASMN1; SMN2 | |
| SCHEMBL15808924 | 0.77 | — | — | |
| SCHEMBL14645934 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL25430450 | 0.76 | TDO2 (0.30) | TDO2KDM4EMEN1KMT2A | |
| SCHEMBL31179854 | 0.76 | TDO2 (0.30) | TDO2KDM4EMEN1KMT2A | |
| SCHEMBL15808892 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809344-B1 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2010-01-20 | — | — | EP | claimed |
| EP-1809344-A2 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | Johnson and Johnson Vision Care, Inc. (US) | 2007-07-25 | — | — | EP | claimed |
| US-7247692-B2 | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2007-07-24 | — | — | US | claimed |
| WO-2006039467-A2 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-04-13 | — | — | WO | claimed |
| US-20060074208-A1 | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE, INC. | 2006-04-06 | — | — | US | claimed |
| EP-2004664-B1 | METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2016-12-14 | — | — | EP | disclosed |
| US-7834205-B2 | Metallocene compounds | Basell Polyolifine GmbH (DE) | 2010-11-16 | — | — | US | disclosed |
| EP-1809344-B1 | BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS | JOHNSON & JOHNSON VISION CARE (US) | 2010-01-20 | — | — | EP | disclosed |
| US-20090275712-A1 | Metallocene Compounds | BASELL POLYOLEFINE GMBH (DE) | 2009-11-05 | — | — | US | disclosed |
| EP-2004664-A1 | METALLOCENE COMPOUNDS | Basell Polyolefine GmbH (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007116034-A1 | METALLOCENE COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |
| US-7247692-B2 | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-20060074208-A1 | Biomedical devices containing amphiphilic block copolymers | JOHNSON & JOHNSON VISION CARE, INC. | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275712-A1 | Metallocene Compounds | MT-CO3, SOD1, MT-CO1 | TDO2 503/4885NPC1 3461/4885LMNA 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.