Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.76 |
| ▸ | HPGD | P15428 | 7/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | AXL | P30530 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20605617 | 0.86 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4ELMNACYP1A2 | |
| SCHEMBL9179370 | 0.79 | GHSR (0.56) | ALDH1A1HPGDKDM4ELMNAGAA | |
| SCHEMBL16442084 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HPGDKDM4ELMNACYP1A2 | |
| SCHEMBL6331432 | 0.78 | KDM4E (0.61) | ALDH1A1HPGDKDM4ELMNACYP1A2 | |
| SCHEMBL394584 | 0.77 | KDM4E (1.00) | ALDH1A1HPGDKDM4ECYP1A2GAA | |
| SCHEMBL30634405 | 0.77 | KDM4E (1.00) | ALDH1A1HPGDKDM4ECYP1A2GAA | |
| SCHEMBL2330779 | 0.77 | KDM4E (0.68) | ALDH1A1HPGDKDM4ECYP1A2GAA | |
| SCHEMBL29533596 | 0.77 | KDM4E (0.68) | ALDH1A1HPGDKDM4ECYP1A2GAA | |
| SCHEMBL6331407 | 0.76 | KDM4E (0.58) | ALDH1A1HPGDKDM4ELMNAGAA | |
| SCHEMBL6534320 | 0.76 | HPGD (0.79) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829578-B1 | Aromatic ketones and uses thereof | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2010-11-09 | — | — | US | disclosed |