SCHEMBL374079

SCHEMBL374079

Cn1cc(C(=O)Nc2ccccc2-c2cc(F)c(Cl)c(F)c2)c(C(F)F)n1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43
NTRK1 P04629 2/20 0.42
ALDH1A1 P00352 3/20 0.41
LMNA P02545 2/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.41
MAPT P10636 1/20 0.41
IRAK4 Q9NWZ3 5/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CHRM3 P20309 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
SSTR2 P30874 1/20 0.39
TSHR P16473 1/20 0.39
LCLAT1 Q6UWP7 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353394 0.93 CHRM3 (0.47) ATMNTRK1ALDH1A1LMNAHTT
SCHEMBL167627 0.93 CHRM3 (0.47) ATMNTRK1ALDH1A1LMNAHTT
SCHEMBL374269 0.92 ATM (0.46) ATMNTRK1ALDH1A1LMNAHTT
SCHEMBL304216 0.92 SSTR2 (0.45) ATMNTRK1ALDH1A1LMNAHTT
SCHEMBL16617799 0.90 CHRM3 (0.44) ATMNTRK1ALDH1A1LMNAHTT
SCHEMBL16864753 0.90 ATM (0.44) ATMNTRK1ALDH1A1LMNAHTT
SCHEMBL4793286 0.89 CHRM3 (0.48) ATMNTRK1ALDH1A1LMNAHTT
SCHEMBL302582 0.89 CHRM3 (0.47) ATMNTRK1ALDH1A1LMNAHTT
SCHEMBL4456706 0.89 CHRM3 (0.51) ATMNTRK1POLBCHRM3TDP1
SCHEMBL121957 0.88 TDP1 (0.53) ATMNTRK1ALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110177944-A1 Synergistic Fungicidal Mixtures BASF SE (DE) 2011-07-21 US claimed
EP-2306832-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2011-04-13 EP claimed
WO-2010072634-A2 POST-HARVEST TREATMENT METHOD BASF SE (DE) 2010-07-01 WO claimed
WO-2009147205-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2009-12-10 WO claimed
US-20250312289-A1 METHODS AND COMPOSITIONS COMPRISING TOBACCO MILD GREEN MOSAIC VIRUS (TMGMV) UNIV CALIFORNIA (US) 2025-10-09 US disclosed
EP-2991490-B1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS BASF SE (DE) 2020-10-14 EP disclosed
EP-3102032-B1 SEED COATING FORMULATIONS AND THEIR USE FOR YIELD INCREASE BASF CORP (US) 2019-04-10 EP disclosed
EP-2192837-B1 FUNGICIDAL MIXTURES OF TRITICONAZOLE AND DIFENOCONAZOLE BASF SE (DE) 2017-05-10 EP disclosed
EP-3102032-A1 Seed coating formulations and their use for yield increase BASF Corporation (US) 2016-12-14 EP disclosed
US-20160345575-A1 Seed Coating Formulations and Their Use for Yield Increase BASF CORPORATION (US) 2016-12-01 US disclosed
EP-2408298-B1 METHOD FOR TREATMENT OF CROP WITH AN ENCAPSULATED PESTICIDE BASF SE (DE) 2016-06-29 EP disclosed
US-20160100576-A1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS BASF SE (DE) 2016-04-14 US disclosed
WO-2010046286-A1 METHOD FOR THE MANUFACTURE OF MICROPARTICLES COMPRISING AN EFFECT SUBSTANCE BASF SE (DE) 2010-04-29 WO disclosed
WO-2010029067-A2 METHOD FOR INCREASING THE NUMBER OF SEEDLINGS PER NUMBER OF SOWED GRAINS OF SEED BASF SE (DE) 2010-03-18 WO disclosed
WO-2009124920-A2 EMULSIFIABLE CONCENTRATE BASF SE (DE) 2009-10-15 WO disclosed
WO-2009071449-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-06-11 WO disclosed
WO-2009071448-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-06-11 WO disclosed
WO-2009065834-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2009-05-28 WO disclosed
WO-2009053250-A1 FUNGICIDAL COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF TO COMBAT DAMAGING FUNGI, AND AGENTS COMPRISING THE SAME BASF SE (DE) 2009-04-30 WO disclosed
WO-2009019176-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177944-A1 Synergistic Fungicidal Mixtures CYP3A5, CYP51A1, CYP3A7 ATM 3679/4885NTRK1 4813/4885ALDH1A1 573/4885
US-20160100576-A1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS DDT, DDC, DERL1 ATM 4477/4885NTRK1 4697/4885ALDH1A1 498/4885
US-20160345575-A1 Seed Coating Formulations and Their Use for Yield Increase CLTB, STUB1, CBLB ATM 729/4885NTRK1 2960/4885ALDH1A1 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.