SCHEMBL374269

SCHEMBL374269

Cc1c(F)cc(-c2ccccc2NC(=O)c2cn(C)nc2C(F)F)cc1F

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
LMNA P02545 2/20 0.42
NTRK1 P04629 2/20 0.42
IRAK4 Q9NWZ3 6/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 3/20 0.41
HTT P42858 2/20 0.41
MAPT P10636 1/20 0.41
CHRM3 P20309 1/20 0.40
TSHR P16473 1/20 0.39
DHODH Q02127 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167627 0.93 CHRM3 (0.47) ATMMEN1KMT2ALMNANTRK1
SCHEMBL29353394 0.93 CHRM3 (0.47) ATMMEN1KMT2ALMNANTRK1
SCHEMBL16864753 0.92 ATM (0.44) ATMMEN1KMT2ALMNANTRK1
SCHEMBL374079 0.92 ATM (0.43) ATMMEN1KMT2ALMNANTRK1
SCHEMBL4793286 0.89 CHRM3 (0.48) ATMMEN1KMT2ALMNANTRK1
SCHEMBL302582 0.89 CHRM3 (0.47) ATMMEN1KMT2ALMNANTRK1
SCHEMBL16617799 0.88 CHRM3 (0.44) ATMMEN1KMT2ALMNANTRK1
SCHEMBL1085490 0.88 ALDH1A1 (0.50) ATMMEN1KMT2ALMNAIRAK4
SCHEMBL304216 0.87 SSTR2 (0.45) ATMLMNANTRK1IRAK4ALDH1A1
SCHEMBL10060307 0.87 LMNA (0.50) ATMMEN1KMT2ALMNANTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2378882-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2011-10-26 EP claimed
US-20110177944-A1 Synergistic Fungicidal Mixtures BASF SE (DE) 2011-07-21 US claimed
WO-2010072634-A2 POST-HARVEST TREATMENT METHOD BASF SE (DE) 2010-07-01 WO claimed
WO-2010069763-A2 SYNERGISTIC FUNGICIDAL MIXTURES BASF SE (DE) 2010-06-24 WO claimed
US-20250312289-A1 METHODS AND COMPOSITIONS COMPRISING TOBACCO MILD GREEN MOSAIC VIRUS (TMGMV) UNIV CALIFORNIA (US) 2025-10-09 US disclosed
EP-2991490-B1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS BASF SE (DE) 2020-10-14 EP disclosed
EP-3102032-B1 SEED COATING FORMULATIONS AND THEIR USE FOR YIELD INCREASE BASF CORP (US) 2019-04-10 EP disclosed
EP-2192837-B1 FUNGICIDAL MIXTURES OF TRITICONAZOLE AND DIFENOCONAZOLE BASF SE (DE) 2017-05-10 EP disclosed
EP-3102032-A1 Seed coating formulations and their use for yield increase BASF Corporation (US) 2016-12-14 EP disclosed
US-20160345575-A1 Seed Coating Formulations and Their Use for Yield Increase BASF CORPORATION (US) 2016-12-01 US disclosed
EP-2408298-B1 METHOD FOR TREATMENT OF CROP WITH AN ENCAPSULATED PESTICIDE BASF SE (DE) 2016-06-29 EP disclosed
US-20160100576-A1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS BASF SE (DE) 2016-04-14 US disclosed
WO-2009124920-A2 EMULSIFIABLE CONCENTRATE BASF SE (DE) 2009-10-15 WO disclosed
WO-2009071449-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-06-11 WO disclosed
WO-2009071448-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-06-11 WO disclosed
WO-2009065834-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2009-05-28 WO disclosed
WO-2009056494-A2 USE OF GLYCEROL, METHOD OF CROP TREATMENT, COMPOSITION FOR TANK MIXING AND A METHOD OF PREPARATION OF A COMPOSITION FOR TANK MIXING BASF SE (DE) 2009-05-07 WO disclosed
WO-2009053250-A1 FUNGICIDAL COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF TO COMBAT DAMAGING FUNGI, AND AGENTS COMPRISING THE SAME BASF SE (DE) 2009-04-30 WO disclosed
WO-2009037162-A2 FUNGICIDAL MIXTURES OF TRITICONAZOLE AND DIFENOCONAZOLE BASF SE (DE) 2009-03-26 WO disclosed
WO-2009019176-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177944-A1 Synergistic Fungicidal Mixtures CYP3A5, CYP51A1, CYP3A7 ATM 3679/4885MEN1 3296/4885KMT2A 3225/4885
US-20160100576-A1 APPLYING A PESTICIDE-COMPRISING DISPERSION OF AN ALIPHATIC POLYURETHANE TO PLANTS DDT, DDC, DERL1 ATM 4477/4885MEN1 2529/4885KMT2A 1648/4885
US-20160345575-A1 Seed Coating Formulations and Their Use for Yield Increase CLTB, STUB1, CBLB ATM 729/4885MEN1 4271/4885KMT2A 1939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.