Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3747320 | 0.84 | ALDH1A1 (0.38) | ALDH1A1MAPK1NPC1LMNAMAPT | |
| SCHEMBL16592547 | 0.82 | ALDH1A1 (0.33) | ALDH1A1MAPK1NPC1LMNAMAPT | |
| SCHEMBL4958672 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPK1NPC1LMNAMAPT | |
| SCHEMBL3747823 | 0.75 | ALOX15 (0.41) | ALDH1A1MAPK1NPC1LMNAMAPT | |
| SCHEMBL3751148 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPK1ALOX15TDP1TSHR | |
| SCHEMBL19950404 | 0.73 | CNR1 (0.50) | ALDH1A1MAPK1NPC1LMNAMAPT | |
| SCHEMBL16592686 | 0.72 | GPR3 (0.35) | ALDH1A1MAPK1NPC1LMNAMAPT | |
| SCHEMBL7599687 | 0.72 | ALOX15 (0.50) | ALDH1A1MAPK1NPC1LMNAMAPT | |
| SCHEMBL434869 | 0.72 | ALOX15 (0.50) | ALDH1A1MAPK1NPC1LMNAMAPT | |
| Cyclopropane SCHEMBL11642163 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPK1NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834120-B2 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1645560-B1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHINETSU CHEMICAL CO (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1645560-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20060074213-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |