SCHEMBL434869

SCHEMBL434869

O=C1OC(=O)c2cc(Cc3ccc4c(c3)C(=O)OC4=O)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 3/20 0.47
TGM2 P21980 1/20 0.42
MAPK1 P28482 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PARP11 Q9NR21 1/20 0.38
TYMS P04818 2/20 0.37
CA1 P00915 2/20 0.35
CA4 P22748 2/20 0.35
CA12 O43570 1/20 0.35
CA7 P43166 1/20 0.35
CA2 P00918 1/20 0.34
CA6 P23280 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL889584 0.92 ALOX15 (0.48) ALOX15TDP1ALDH1A1LMNAPARP11
SCHEMBL19927918 0.89 ALDH1A1 (0.40) ALOX15TDP1ALDH1A1TGM2MAPK1
SCHEMBL23625252 0.89 TDP1 (0.40) ALOX15TDP1ALDH1A1TGM2MAPK1
SCHEMBL14492052 0.89 TDP1 (0.40) ALOX15TDP1ALDH1A1TGM2MAPK1
SCHEMBL13883791 0.87 ALOX15 (0.39) ALOX15TDP1ALDH1A1TGM2MAPK1
SCHEMBL7599687 0.86 ALOX15 (0.50) ALOX15TDP1ALDH1A1MAPK1NPC1
SCHEMBL29340028 0.85 ALDH1A1 (0.36) ALOX15TDP1ALDH1A1TGM2MAPK1
SCHEMBL25992001 0.84 ALDH1A1 (0.37) ALOX15TDP1ALDH1A1TGM2MAPK1
SCHEMBL9602115 0.83 CA12 (0.39) ALOX15TDP1ALDH1A1LMNAMAPT
SCHEMBL4547146 0.83 ALOX15 (0.46) ALOX15TDP1ALDH1A1MAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11879039-B1 Preparation method for thermoplastic multi-hybrid polyimide films HARBIN ENGINEERING UNIVERSITY (CN) 2024-01-23 US claimed
CN-115216009-B Preparation method of thermoplastic multi-component hybrid polyimide film 哈尔滨工程大学 2023-05-30 CN claimed
US-10059682-B1 Asymmetric dianhyrdrides and methods of making the same THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2018-08-28 US claimed
EP-2658897-A1 AMINO FUNCTIONALISED OLIGOIMIDES WITH ENHANCED STORAGE STABILITY Director General, Defence Research & Development Organisation (IN) 2013-11-06 EP claimed
WO-2012090055-A1 AMINO FUNCTIONALISED OLIGOIMIDES WITH ENHANCED STORAGE STABILITY DIRECTOR GENERAL, DEFENCE RESEARCH & DEVELOPMENT ORGANISATION (IN) 2012-07-05 WO claimed
US-7005163-B2 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2006-02-28 US claimed
US-20040110014-A1 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2004-06-10 US claimed
US-5047487-A And polyetherimide copolymers; integrated circuits, semconductors RAYCHEM CORPORATION (US) 1991-09-10 US claimed
CN-114479450-B Homogeneous heterogeneous polyimide film and preparation method and application thereof 中国石油化工股份有限公司 2025-03-04 CN disclosed
WO-2024062865-A1 2-CYANOACRYLATE ADHESIVE COMPOSITION 田岡化学工業株式会社 2024-03-28 WO disclosed
US-11879039-B1 Preparation method for thermoplastic multi-hybrid polyimide films HARBIN ENGINEERING UNIVERSITY (CN) 2024-01-23 US disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-20230317312-A1 THERMALLY CONDUCTIVE FLAT SELF-FUSING ENAMELED WIRE JUNG SHING WIRE CO., LTD. (TW) 2023-10-05 US disclosed
EP-0119162-A2 Photopolymerisable composition, material coated therewith, and process for obtaining relief images CIBA-GEIGY AG (CH) 1984-09-19 EP disclosed
EP-0099338-A1 Epoxy resin systems modified with thermoplastic resins CIBA-GEIGY AG (CH) 1984-01-25 EP disclosed
EP-0098681-A2 Novel dinitrobenzophenone solution and process for preparing an ether solution of diaminobenzophenones therefrom CHEVRON RESEARCH COMPANY (US) 1984-01-18 EP disclosed
EP-0092524-A2 Radiation-sensible coating composition and its use CIBA-GEIGY AG (CH) 1983-10-26 EP disclosed
EP-0084406-A1 Ophthalmic device comprising a polymer of a telechelic perfluoropolyether MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-07-27 EP disclosed
US-4080319-A Elastomeric copolymides containing fluorine and process for preparing same MONTEDISON S.P.A. (IT) 1978-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10059682-B1 Asymmetric dianhyrdrides and methods of making the same BTD, AASDHPPT, ACMSD ALOX15 1543/4885TDP1 3085/4885ALDH1A1 689/4885
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound PRMT9, PRMT1, PNMT ALOX15 4463/4885TDP1 2677/4885ALDH1A1 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.