Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3744663 | 0.88 | HSD11B1 (0.48) | HSD11B1CYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL3749435 | 0.88 | LMNA (0.46) | HSD11B1CYP3A4USP2CYP1A2CYP2D6 | |
| SCHEMBL3747454 | 0.78 | POLB (0.48) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3749402 | 0.72 | CYP2D6 (0.43) | HSD11B1CYP3A4CYP2D6KMT2AALDH1A1 | |
| SCHEMBL3757096 | 0.72 | HSD11B1 (0.53) | HSD11B1CYP3A4USP2CYP1A2CYP2D6 | |
| SCHEMBL3744641 | 0.71 | HSD11B1 (0.47) | HSD11B1CYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL2699791 | 0.70 | KMT2A (0.76) | HSD11B1CYP3A4USP2CYP1A2CYP2D6 | |
| SCHEMBL11888962 | 0.69 | PKM (0.65) | HSD11B1CYP3A4USP2CYP1A2CYP2D6 | |
| SCHEMBL3742454 | 0.69 | HSD11B1 (0.44) | HSD11B1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL12549973 | 0.69 | HSD11B1 (1.00) | HSD11B1CYP3A4USP2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298368-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298368-A1 | ANTAGONISTS OF PGD2 RECEPTORS | PTGDR2, PTGDR, LTB4R2 | HSD11B1 442/4885CYP3A4 3168/4885USP2 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.