Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683086 | 0.81 | SMN1; SMN2 (0.43) | HPGDALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL31033488 | 0.76 | PARP1 (0.56) | HPGDALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL353892 | 0.76 | PARP1 (0.56) | HPGDALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL18757861 | 0.75 | RAB9A (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Bromide SCHEMBL5318093 | 0.75 | PARP1 (0.55) | HPGDALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL13405981 | 0.74 | NPC1 (0.69) | HPGDALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL6759198 | 0.74 | ADORA3 (0.40) | HPGDALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL2578466 | 0.74 | NPC1 (0.46) | HPGDALDH1A1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL6939187 | 0.74 | PIM1 (0.47) | SMN1; SMN2NPC1RAB9AKDM4EPARP1 | |
| SCHEMBL6139628 | 0.73 | DAO (0.43) | HPGDALDH1A1SMN1; SMN2NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948728-B1 | IMPROVED LEAD-FREE INSULATION COMPOSITIONS CONTAINING METALLOCENE POLYMERS | GEN CABLE TECHNOLOGIES CORP (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-2410010-B1 | Improved lead-free insulation compositions containing metallocene polymers | GEN CABLE TECHNOLOGIES CORP (US) | 2019-03-13 | — | — | EP | disclosed |
| EP-2311049-B1 | IMPROVED HARD GRADE EPR INSULATION COMPOSITIONS | GEN CABLE TECHNOLOGIES CORP (US) | 2014-08-27 | — | — | EP | disclosed |
| EP-2410010-A1 | Improved lead-free insulation compositions containing metallocene polymers | General Cable Technologies Corporation (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-2311049-A2 | IMPROVED HARD GRADE EPR INSULATION COMPOSITIONS | General Cable Technologies Corporation (US) | 2011-04-20 | — | — | EP | disclosed |
| US-7858711-B2 | Lead-free insulation compositions containing metallocene polymers | General CableTechnologies Corporation (US) | 2010-12-28 | — | — | US | disclosed |
| WO-2010011418-A2 | IMPROVED HARD GRADE EPR INSULATION COMPOSITIONS | GENERAL CABLE TECHNOLOGIES CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |
| US-20100022683-A1 | HARD GRADE EPR INSULATION COMPOSITIONS | GENERAL CABLE TECHNOLOGIES CORPORATION (US) | 2010-01-28 | — | — | US | disclosed |
| US-7473742-B2 | Lead-free insulation compositions containing metallocene polymers | GENERAL CABLE TECHNOLOGIES CORP. (US) | 2009-01-06 | — | — | US | disclosed |
| EP-1948728-A2 | IMPROVED LEAD-FREE INSULATION COMPOSITIONS CONTAINING METALLOCENE POLYMERS | General Cable Technologies Corporation (US) | 2008-07-30 | — | — | EP | disclosed |
| US-20070213433-A1 | Polymer may be metallocene based, non metallocene based, hindered amine light stabilizers, mercapto compounds, and optionally, amine antioxidants, improved electrical and mechanical properties; without use of custom polymers such as elastomer terpolymer containing 5-vinyl-2-norbornene as base resin | GENERAL CABLE TECHNOLOGIES CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070100032-A1 | Lead-free insulation compositions containing metallocene polymers | GENERAL CABLE TECHNOLOGIES CORPORATION | 2007-05-03 | — | — | US | disclosed |
| WO-2007050688-A2 | IMPROVED LEAD-FREE INSULATION COMPOSITIONS CONTAINING METALLOCENE POLYMERS | GENERAL CABLE TECHNOLOGIES CORPORATION (US) | 2007-05-03 | — | — | WO | disclosed |