Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374824 | 0.81 | HPGD (0.42) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL5142221 | 0.77 | PARP1 (0.59) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL22648457 | 0.76 | PARP1 (0.39) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL23278130 | 0.76 | CA12 (0.42) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL18757861 | 0.75 | RAB9A (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1PARP1 | |
| SCHEMBL6939187 | 0.74 | PIM1 (0.47) | SMN1; SMN2NPC1RAB9APARP1KDM4E | |
| SCHEMBL27500905 | 0.74 | ALDH1A1 (0.39) | SMN1; SMN2LMNAALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9306736 | 0.73 | CA12 (0.40) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL9305632 | 0.73 | CA12 (0.40) | SMN1; SMN2NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL31122397 | 0.73 | NUDT1 (0.48) | NPC1RAB9AALDH1A1PARP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189830-B2 | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2019-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189830-B2 | Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders | NQO1, COQ8A, NDUFAB1 | SMN1; SMN2 303/4885NPC1 551/4885RAB9A 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.