Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999038 | 0.88 | PAM (0.78) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL3673828 | 0.84 | PAM (0.72) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL4947133 | 0.84 | PAM (0.72) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL4947139 | 0.84 | PAM (0.72) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL1434644 | 0.83 | ALDH1A1 (0.73) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL10525631 | 0.82 | ALDH1A1 (0.85) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6988546 | 0.82 | PAM (0.70) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL7716471 | 0.82 | KMT2A (0.79) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL30952004 | 0.81 | PAM (0.68) | PAMALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL27338367 | 0.81 | PAM (0.68) | PAMALDH1A1MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207972-A1 | Propylene polymer catalyst donor component | INEOS USA LLC | 2008-08-28 | — | — | US | claimed |
| EP-1863855-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INEOS USA LLC (US) | 2007-12-12 | — | — | EP | claimed |
| US-20070179047-A1 | Propylene polymer catalyst donor component | INNOVENE USA (US) | 2007-08-02 | — | — | US | claimed |
| WO-2006096621-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INNOVENE USA LLC (US) | 2006-09-14 | — | — | WO | claimed |
| US-5643949-A | Phenyl alpha acyloxyalkanoic acids, derivatives and their therapeutic use | TRISTRATA, INC. (US) | 1997-07-01 | — | — | US | claimed |
| US-20140058129-A1 | Phenylacetic Acid Derivatives | NOVARTIS AG (CH) | 2014-02-27 | — | — | US | disclosed |
| US-8586782-B2 | Phenylacetic acid derivatives | NOVARTIS AG (CH) | 2013-11-19 | — | — | US | disclosed |
| US-8362294-B2 | Phenylacetic acid derivatives | NOVARTIS AG (CH) | 2013-01-29 | — | — | US | disclosed |
| US-20130012585-A1 | Phenylacetic Acid Derivatives | MONOVICH LAUREN G (US) | 2013-01-10 | — | — | US | disclosed |
| EP-2046723-B1 | PHENYLACETIC ACID DERIVATIVES AS COX-2 INHIBITORS | NOVARTIS AG (CH) | 2012-07-18 | — | — | EP | disclosed |
| US-7674943-B2 | Solid, hydrocarbon-insoluble, catalyst component containing magnesium, titanium, and halogen, and further contains an internal electron donor which does not contain a phthalate derivative, for example, ethyl (phenylacetoxy)acetate; stereospecific polymerization; highly crystalline propylene polymers | INEOS USA LLC (US) | 2010-03-09 | — | — | US | disclosed |
| EP-1567477-B1 | SUBSTITUTED AMINO PHENYLACETIC ACIDS, DERIVATIVES THEREOF, THEIR PREPARATION AND THEIR USE AS CYCLOOXYGENASE 2 (COX-2) INHIBITORS | NOVARTIS AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| US-20070179047-A1 | Propylene polymer catalyst donor component | INNOVENE USA (US) | 2007-08-02 | — | — | US | disclosed |
| US-7202364-B2 | Certain phenylacetic acids and derivatives | NOVARTIS, AG (CH) | 2007-04-10 | — | — | US | disclosed |
| WO-2006096621-A2 | PROPYLENE POLYMER CATALYST DONOR COMPONENT | INNOVENE USA LLC (US) | 2006-09-14 | — | — | WO | disclosed |
| EP-1567477-A1 | SUBSTITUTED AMINO PHENYLACETIC ACIDS, DERIVATIVES THEREOF, THEIR PREPARATION AND THEIR USE AS CYCLOOXYGENASE 2 (COX-2) INHIBITORS | Novartis AG (CH) | 2005-08-31 | — | — | EP | disclosed |
| US-20040132769-A1 | Certain phenylacetic acids and derivatives | NOVARTIS AG (CH) | 2004-07-08 | — | — | US | disclosed |
| WO-2004048314-A1 | SUBSTITUTED AMINO PHENYLACETIC ACIDS, DERIVATIVES THEREOF, THEIR PREPARATION AND THEIR USE AS CYCLOOXYGENASE 2 (COX-2) INHIBITORS | NOVARTIS AG (CH) | 2004-06-10 | — | — | WO | disclosed |
| EP-0738706-A1 | Nitric esters of 2-(2,6-dihalophenylamino) phenylacetoxyacetic acid derivatives and their preparation process | PRODES, S.A. (ES) | 1996-10-23 | — | — | EP | disclosed |
| US-5258391-A | Phenyl alpha acyloxyalkanoic acids, derivatives and their therapeutic use | TRISTRATA, INC. | 1993-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140058129-A1 | Phenylacetic Acid Derivatives | PTGES2, PTGS2, GOT2 | PAM 2290/4885ALDH1A1 37/4885MAPK1 2327/4885 |
| US-20040132769-A1 | Certain phenylacetic acids and derivatives | CYP2A6, HCAR2, CYP2B6 | PAM 1773/4885ALDH1A1 99/4885MAPK1 1188/4885 |
| US-20130012585-A1 | Phenylacetic Acid Derivatives | PTGES2, PTGS2, GOT2 | PAM 2290/4885ALDH1A1 37/4885MAPK1 2327/4885 |
| US-20080207972-A1 | Propylene polymer catalyst donor component | RAD52, NR2C2, PGR | PAM 1033/4885ALDH1A1 4642/4885MAPK1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.