Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317430 | 0.83 | CRHR1 (0.39) | CRHR1PDK2ACHECYP1A2CYP2A6 | |
| SCHEMBL7896719 | 0.78 | CRHR1 (0.39) | CRHR1PDK2ACHECYP1A2CYP2A6 | |
| SCHEMBL7899006 | 0.78 | CRHR1 (0.36) | CRHR1PDK2ACHECYP1A2CYP2A6 | |
| SCHEMBL7908991 | 0.78 | CRHR1 (0.36) | CRHR1PDK2ACHECYP1A2CYP2A6 | |
| SCHEMBL8038390 | 0.75 | LMNA (0.43) | CRHR1PDK2CYP1A2CYP2A6KDM4E | |
| SCHEMBL11552812 | 0.74 | ACHE (0.45) | ACHECYP1A2CYP2A6ALDH1A1KDM4E | |
| SCHEMBL6745620 | 0.74 | ALDH1A1 (0.44) | CRHR1PDK2ACHEALDH1A1KDM4E | |
| SCHEMBL16050969 | 0.74 | CRHR1 (0.39) | CRHR1PDK2ACHECYP1A2CYP2A6 | |
| SCHEMBL9509317 | 0.74 | RAPGEF4 (0.47) | CRHR1PDK2ACHECYP1A2CYP2A6 | |
| SCHEMBL16219593 | 0.74 | RAPGEF4 (0.40) | CRHR1PDK2ACHECYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833443-B2 | Molds for producing contact lenses | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-11-16 | — | — | US | disclosed |