Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL10383285 | 1.00 | TSHR (0.55) | TSHRTP53MEN1KMT2ARARB | |
| Terephthalic Acid SCHEMBL27506116 | 1.00 | TSHR (0.55) | TSHRTP53MEN1KMT2ARARB | |
| Tetraethylene Glycol SCHEMBL3841162 | 1.00 | TSHR (0.55) | TSHRTP53MEN1KMT2ARARB | |
| Terephthalic Acid SCHEMBL31548541 | 0.98 | TSHR (0.52) | TSHRTP53MEN1KMT2ARARB | |
| Terephthalic Acid SCHEMBL375131 | 0.98 | TSHR (0.57) | TSHRTP53MEN1KMT2ARARB | |
| Terephthalic Acid SCHEMBL6554172 | 0.98 | TSHR (0.57) | TSHRTP53MEN1KMT2ARARB | |
| Terephthalic Acid SCHEMBL9165497 | 0.95 | TSHR (0.55) | TSHRTP53MEN1KMT2ARARB | |
| Paraben SCHEMBL3364114 | 0.92 | CA2 (0.61) | TSHRTP53MEN1KMT2ARARB | |
| Triethylene Glycol SCHEMBL5730892 | 0.91 | TSHR (0.58) | TSHRTP53MEN1KMT2ARARB | |
| Triethylene Glycol SCHEMBL205789 | 0.91 | TSHR (0.58) | TSHRTP53MEN1KMT2ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130046039-A1 | PROCESS FOR PREPARING THERMOPLASTIC ELASTOMER COMPOSITION AND MOLDED PRODUCT | MITSUI CHEMICALS, INC. | 2013-02-21 | — | — | US | claimed |
| US-20240228759-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, MOLDED ARTICLE THEREOF, AND USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2024-07-11 | — | — | US | disclosed |
| EP-4361215-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, MOLDED BODY THEREOF, AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-117545802-A | Thermoplastic elastomer composition, molded body thereof and use thereof | 三井化学株式会社 | 2024-02-09 | — | — | CN | disclosed |
| WO-2022270572-A1 | THERMOPLASTIC ELASTOMER COMPOSITION, MOLDED BODY THEREOF, AND USE THEREOF | 三井化学株式会社 | 2022-12-29 | — | — | WO | disclosed |
| US-20210230415-A1 | POLYMER COMPOSITION AND USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2021-07-29 | — | — | US | disclosed |
| EP-3725842-A1 | POLYMER COMPOSITION AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2020-10-21 | — | — | EP | disclosed |
| CN-111448253-A | Polymer composition and use thereof | 三井化学株式会社 | 2020-07-24 | — | — | CN | disclosed |
| EP-2169003-B1 | THERMOPLASTIC ELASTOMER COMPOSITION | MITSUI CHEMICALS INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-20130046039-A1 | PROCESS FOR PREPARING THERMOPLASTIC ELASTOMER COMPOSITION AND MOLDED PRODUCT | MITSUI CHEMICALS, INC. | 2013-02-21 | — | — | US | disclosed |
| CN-101679702-B | Thermoplastic elastomer composition | MTHEUI CHEMICALS INC | 2012-07-04 | — | — | CN | disclosed |
| US-8063146-B2 | Thermoplastic elastomer composition | MITSUI CHEMICALS, INC. (JP) | 2011-11-22 | — | — | US | disclosed |
| US-20100120933-A1 | THERMOPLASTIC ELASTOMER COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-05-13 | — | — | US | disclosed |
| US-20100105790-A1 | PROCESS FOR PREPARING THERMOPLASTIC ELASTOMER COMPOSITION AND MOLDED PRODUCT | MITSUI CHEMICALS, INC. | 2010-04-29 | — | — | US | disclosed |
| EP-2169003-A1 | THERMOPLASTIC ELASTOMER COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2010-03-31 | — | — | EP | disclosed |
| CN-101679702-A | Thermoplastic elastomer composition | MTHEUI CHEMICALS INC | 2010-03-24 | — | — | CN | disclosed |
| EP-2154193-A1 | METHOD OF PRODUCING THERMOPLASTIC ELASTOMER COMPOSITION AND MOLDED ARTICLE | Mitsui Chemicals, Inc. (JP) | 2010-02-17 | — | — | EP | disclosed |
| US-4340721-A | IN THE PRESENCE OF CRYSTAL GROWTH INHIBITORS | RHONE-POULENC INDUSTRIES (FR) | 1982-07-20 | — | — | US | disclosed |
| US-4233355-A | POLYESTERS AND POLYAMIDES | TORAY INDUSTRIES, INC. (JP) | 1980-11-11 | — | — | US | disclosed |
| US-4055613-A | Production of three-dimensional designs | AKROSIL CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |