SCHEMBL375164

SCHEMBL375164

CC1CCCc2c(C(N)=O)ccc(C(N)=O)c2C1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.41
HTR1A P08908 1/20 0.40
GAA P10253 2/20 0.39
ALDH1A1 P00352 5/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
NNMT P40261 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TP53 P04637 1/20 0.36
BTK Q06187 1/20 0.35
NPC1 O15118 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16892762 0.94 PARP1 (0.39) PARP1HTR1AGAAALDH1A1KDM4E
SCHEMBL3258685 0.83 MAPT (0.40) PARP1HTR1AGAAALDH1A1KDM4E
SCHEMBL1160668 0.78 HSD17B10 (0.47) PARP1HTR1AALDH1A1KDM4EMAPT
SCHEMBL5459284 0.76 HSD17B10 (0.46) PARP1HTR1AALDH1A1KDM4EMAPT
SCHEMBL35972 0.76 HSD17B10 (0.46) PARP1HTR1AALDH1A1KDM4EMAPT
SCHEMBL919063 0.76 HSD17B10 (0.46) PARP1HTR1AALDH1A1KDM4EMAPT
SCHEMBL8708889 0.76 HSD17B10 (0.46) PARP1HTR1AALDH1A1KDM4EMAPT
SCHEMBL16739249 0.76 HSD17B10 (0.46) PARP1HTR1AALDH1A1KDM4EMAPT
SCHEMBL35787 0.76 HSD17B10 (0.46) PARP1HTR1AALDH1A1KDM4EMAPT
SCHEMBL4556902 0.76 HSD17B10 (0.46) PARP1HTR1AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3564319-B1 POLYAMIDE RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED THEREFROM LOTTE ADVANCED MAT CO LTD (KR) 2024-03-13 EP claimed
EP-2949693-B1 A THERMOPLASTIC RESIN COMPOSITION FOR AUTOMOBILES AND A MOLDED PRODUCT PRODUCED FROM THE SAME LOTTE ADVANCED MAT CO LTD (KR) 2018-09-12 EP claimed
EP-3034558-B1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED PART FOR AUTOMOBILES USING THE SAME LOTTE ADVANCED MAT CO LTD (KR) 2017-07-19 EP claimed
EP-2371903-A2 Gear for an electric power steering device the gear comprising a polyamide composition E. I. du Pont de Nemours and Company (US) 2011-10-05 EP claimed
US-7999018-B2 blends of polyamides or polyesters, metal alloys, carbon fibers and metal powders, in the form an electrical or electronic housing, a motor core housing or secondary battery cases, having high stiffness E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-16 US claimed
EP-1971642-B1 CARBON FIBER REINFORCED POLYAMIDE RESIN COMPOSITION DU PONT (US) 2010-03-31 EP claimed
EP-2061838-A2 POLYAMIDE RESIN COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-27 EP claimed
JP-2008540777-A 2008-11-20 JP claimed
WO-2008134030-A1 THERMOPLASTIC RESIN COMPOSITION HAVING ELECTROMAGNETIC INTERFERENCE SHIELDING PROPERTIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-11-06 WO claimed
US-20080269378-A1 Thermoplastic resin composition having electromagnetic interference shielding properties CELANESE POLYMERS HOLDING, INC. 2008-10-30 US claimed
EP-1971642-A1 CARBON FIBER REINFORCED POLYAMIDE RESIN COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-24 EP claimed
WO-2008030600-A2 POLYAMIDE RESIN COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-13 WO claimed
US-20080064826-A1 Comprising at least one polyamide component, glass fibers, and at least one polycarbodiimide component; good impact resistance as well as good stiffness, toughness E. I. DU PONT DE NEMOURS AND COMPANY 2008-03-13 US claimed
EP-1879963-A1 POLYAMIDE RESIN COMPOSITION E.I. DUPONT DE NEMOURS AND COMPANY (US) 2008-01-23 EP claimed
US-20070155877-A1 Polyamide resin composition E. I. DU PONT DE NEMOURS AND COMPANY 2007-07-05 US claimed
WO-2007061965-A1 CARBON FIBER REINFORCED POLYAMIDE RESIN COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-31 WO claimed
US-20070021558-A1 Polyamide resin composition SHINOHARA KENICHI 2007-01-25 US claimed
WO-2006124659-A1 POLYAMIDE RESIN COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-11-23 WO claimed
US-11993713-B2 Polyamide resin composition and method for producing same TOYOBO MC CORPORATION (JP) 2024-05-28 US disclosed
US-4163101-A HEATING AN AQUEOUS SOLUTION OF THE CORRESPONDING SALT DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-07-31 US disclosed