Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 9/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617550 | 0.76 | ALDH1A1 (0.47) | TLR2TLR1ALDH1A1KMT2ALMNA | |
| SCHEMBL20085597 | 0.74 | ALDH1A1 (0.47) | TLR2TLR1ALDH1A1KMT2ALMNA | |
| SCHEMBL8822076 | 0.74 | ALDH1A1 (0.47) | TLR2TLR1ALDH1A1KMT2ALMNA | |
| SCHEMBL3752669 | 0.73 | TLR2 (0.39) | TLR2TLR1ALDH1A1KMT2ALMNA | |
| SCHEMBL4015948 | 0.73 | ALDH1A1 (0.41) | TLR2TLR1ALDH1A1KMT2ALMNA | |
| SCHEMBL4019860 | 0.72 | ALDH1A1 (0.45) | TLR2TLR1ALDH1A1KMT2ALMNA | |
| SCHEMBL5924431 | 0.71 | NR2E1 (0.31) | — | |
| SCHEMBL11901049 | 0.71 | TLR2 (0.48) | TLR2TLR1ALDH1A1KMT2A | |
| SCHEMBL3745954 | 0.71 | ALDH1A1 (0.44) | TLR2TLR1ALDH1A1KMT2ALMNA | |
| SCHEMBL3433157 | 0.70 | ALDH1A1 (0.41) | TLR2TLR1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298384-A1 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-11-25 | — | — | US | disclosed |
| WO-2008143649-A2 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-11-27 | — | — | WO | disclosed |
| US-20060270628-A1 | Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. | 2006-11-30 | — | — | US | disclosed |
| WO-2004101531-A1 | ANTIINFECTIVE 1,2,3-TRIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270628-A1 | Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them | IL33, IL5, IL1B | TLR2 161/4885TLR1 25/4885ALDH1A1 1498/4885 |
| US-20100298384-A1 | NOVEL OXAZOLIDINONE COMPOUNDS AS ANTIINFECTIVE AGENTS | OXA1L, MIF, VIP | TLR2 266/4885TLR1 125/4885ALDH1A1 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.