SCHEMBL5924431

SCHEMBL5924431

CC(C)(C)[SiH2]OC(C)(C)c1cn(-c2c(F)cc(N)cc2F)cn1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR2E1 Q9Y466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3747437 0.85 ALDH1A1 (0.32)
SCHEMBL2173933 0.75 CPB2 (0.32)
SCHEMBL3752676 0.71 TLR2 (0.39)
SCHEMBL2254115 0.70 NR2E1 (0.53) NR2E1
SCHEMBL3753825 0.67 MAOA (0.41)
SCHEMBL5924427 0.67 NR2E1 (0.31) NR2E1
SCHEMBL960744 0.67 NR2E1 (0.33) NR2E1
SCHEMBL6707053 0.66 GRM5 (0.36)
SCHEMBL5924424 0.65
SCHEMBL3387689 0.62 KDM4E (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060270628-A1 Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them DR. REDDY'S LABORATORIES, INC. 2006-11-30 US disclosed
WO-2004101531-A1 ANTIINFECTIVE 1,2,3-TRIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2004-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060270628-A1 Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them IL33, IL5, IL1B NR2E1 622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.