Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760427 | 0.82 | ALDH1A1 (0.45) | PDE2AALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL29402881 | 0.78 | TSHR (0.61) | PDE2AALDH1A1MAPTMEN1TSHR | |
| SCHEMBL980201 | 0.78 | TSHR (0.61) | PDE2AALDH1A1MAPTMEN1TSHR | |
| Ammonia Solution, Strong SCHEMBL28020319 | 0.76 | TSHR (0.58) | PDE2AALDH1A1MAPTMEN1TSHR | |
| SCHEMBL19785361 | 0.76 | PDE2A (0.52) | PDE2AALDH1A1MAPTTSHRAHR | |
| SCHEMBL5537111 | 0.74 | CES2 (0.55) | ALDH1A1MEN1TSHRKMT2ADAO | |
| SCHEMBL2839879 | 0.74 | PDE2A (0.47) | PDE2AALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL3028480 | 0.74 | PDE2A (0.42) | PDE2AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3822269 | 0.74 | PDE2A (0.50) | PDE2AALDH1A1MAPTMEN1TSHR | |
| SCHEMBL3789260 | 0.74 | PDE2A (0.56) | PDE2AALDH1A1MAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979887-A | Synthetic method of aromatic amine carboxylic acid derivative | 北京亦农生物科技有限公司 | 2022-01-28 | — | — | CN | claimed |
| US-9061967-B2 | Substituted diphenylamine compounds, preparation method and use thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2015-06-23 | — | — | US | claimed |
| EP-2826474-A1 | USE OF SUBSTITUTED DIPHENYLAMINE COMPOUNDS IN PREPARING ANTI-TUMOUR DRUGS | Sinochem Corporation (CN) | 2015-01-21 | — | — | EP | claimed |
| US-20150011628-A1 | SUBSTITUTE DIPHENYLAMINE COMPOUNDS USE THEREOF AS ANTITUMOR AGENTS | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2015-01-08 | — | — | US | claimed |
| EP-2551258-A1 | SUBSTITUTED DIPHENYLAMINE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | Sinochem Corporation (CN) | 2013-01-30 | — | — | EP | claimed |
| US-20120309844-A1 | Substituted Diphenylamine Compounds, Preparation Method and Use Thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2012-12-06 | — | — | US | claimed |
| CN-1363548-A | Bietherifying process for synthesizing oxyfluorfen | LANXI AGRICULTURLA CHEMICAL FA (NC) | 2002-08-14 | — | — | CN | claimed |
| EP-1148056-A1 | Herbicidal benzoyloxy carboxylates and carboxamides | Dow AgroSciences LLC (US) | 2001-10-24 | — | — | EP | claimed |
| US-6251829-B1 | PREEMERGENT AND POSTEMERGENT HERBICIDES | ROHM AND HAAS COMPANY | 2001-06-26 | — | — | US | claimed |
| CN-1253593-A | Expression of herbicide binding polypeptides in plants to confer herbicide tolerance | BASF AG (DE) | 2000-05-17 | — | — | CN | claimed |
| US-5155135-A | Insecticides, miticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B.V. (NL) | 1992-10-13 | — | — | US | claimed |
| CN-1043702-A | Benzamide compounds, its preparation method and as the application of sterilant | SHELL INT RESEARCH (NL) | 1990-07-11 | — | — | CN | claimed |
| EP-0375069-A1 | Benzamide compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-06-27 | — | — | EP | claimed |
| EP-0261459-A2 | N-benzothiazolyl amides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-03-30 | — | — | EP | claimed |
| EP-0103918-B1 | PESTICIDAL BENZOYLUREA COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-07-29 | — | — | EP | claimed |
| EP-0093976-B1 | 2,4-DIHALOGENBENZOYL UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1986-09-10 | — | — | EP | claimed |
| US-4517193-A | INSECTICIDES, MITICIDES | SHELL OIL COMPANY (US) | 1985-05-14 | — | — | US | claimed |
| US-4497822-A | Insecticidal N-benzoyl-N'-phenyl-N'-(R-thio)ureas | SHELL OIL COMPANY (US) | 1985-02-05 | — | — | US | claimed |
| US-4493730-A | Phenoxypyridine useful as a herbicide | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1985-01-15 | — | — | US | claimed |
| EP-0103918-A2 | Pesticidal benzoylurea compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-03-28 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309844-A1 | Substituted Diphenylamine Compounds, Preparation Method and Use Thereof | DDT, DPM1, CYP3A7 | PDE2A 595/4885ALDH1A1 321/4885MAPT 3075/4885 |
| US-20150011628-A1 | SUBSTITUTE DIPHENYLAMINE COMPOUNDS USE THEREOF AS ANTITUMOR AGENTS | MCL1, BRCA1, FLI1 | PDE2A 3294/4885ALDH1A1 91/4885MAPT 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.