Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | BCAT2 | O15382 | 7/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 7/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28853728 | 0.76 | BCAT2 (0.34) | NOTUMARKDM4EALDH1A1GLA | |
| SCHEMBL10590631 | 0.75 | AR (0.54) | ARKDM4EALDH1A1GLAGAA | |
| SCHEMBL27349760 | 0.72 | AR (0.52) | ARBCAT2BCAT1 | |
| SCHEMBL27306662 | 0.72 | KDM4E (0.34) | NOTUMKDM4EALDH1A1GLAGAA | |
| SCHEMBL9381741 | 0.72 | NOTUM (0.53) | NOTUMARKDM4EALDH1A1GAA | |
| SCHEMBL6466233 | 0.72 | — | — | |
| SCHEMBL5369669 | 0.71 | KIF11 (0.46) | NOTUMARKDM4EALDH1A1GLA | |
| SCHEMBL9193868 | 0.71 | MAOA (0.45) | ARKDM4EALDH1A1GLAGAA | |
| SCHEMBL25805750 | 0.70 | NOTUM (0.52) | NOTUMKDM4EALDH1A1HPGDBCAT2 | |
| SCHEMBL5330560 | 0.70 | AR (0.39) | ARKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103539716-A | One group of 2-para chlorphenyl-4-substituted methyl-5- trifluoromethyl-3-cyanpyrrole compounds | UNIV QINGDAO AGRICULTURAL | 2014-01-29 | — | — | CN | claimed |
| CN-103539716-A | One group of 2-para chlorphenyl-4-substituted methyl-5- trifluoromethyl-3-cyanpyrrole compounds | UNIV QINGDAO AGRICULTURAL | 2014-01-29 | — | — | CN | disclosed |
| US-8222274-B2 | Pyrrole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-07-17 | — | — | US | disclosed |
| EP-1988075-B1 | PYRROLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-01-25 | — | — | EP | disclosed |
| US-20090036421-A1 | Pyrrole Derivative or Salt Thereof | ASTELLAS PHARMA INC (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1988075-A1 | PYRROLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036421-A1 | Pyrrole Derivative or Salt Thereof | HTR7, HTR2B, SSTR5 | NOTUM 1067/4885AR 2712/4885KDM4E 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.