SCHEMBL3759210

SCHEMBL3759210

Cc1ccc([I+](OS(=O)(=O)C(F)(F)C(F)(F)F)c2ccc(CC(C)C)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 2/20 0.33
POLB P06746 2/20 0.33
PTGS2 P35354 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BCHE P06276 2/20 0.32
ACHE P22303 2/20 0.32
PTGS1 P23219 2/20 0.32
ALOX5 P09917 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
CXCR1 P25024 2/20 0.32
CXCR2 P25025 2/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3762386 0.91 CA1 (0.38) ALDH1A1KDM4EPOLBPTGS2SMN1; SMN2
SCHEMBL3764393 0.79 ALDH1A1 (0.43) ALDH1A1KDM4EPOLBPTGS2SMN1; SMN2
SCHEMBL3762396 0.79 TSHR (0.43) ALDH1A1SMN1; SMN2BCHEACHECA1
SCHEMBL2898700 0.77 CA2 (0.39) ALDH1A1PTGS2SMN1; SMN2BCHEACHE
SCHEMBL3755833 0.77 NPC1 (0.35) ALDH1A1SMN1; SMN2BCHEACHECA1
SCHEMBL2895496 0.76 CA2 (0.38) ALDH1A1CA1CA2CA9
SCHEMBL3759102 0.76 BCHE (0.43) ALDH1A1KDM4EPOLBSMN1; SMN2BCHE
SCHEMBL2897585 0.75 CA2 (0.39) CA1CA2CA9
SCHEMBL3762373 0.74 NR3C1 (0.45) ALDH1A1KDM4EPOLBSMN1; SMN2MEN1
SCHEMBL3756892 0.73 BCHE (0.43) ALDH1A1KDM4EPOLBSMN1; SMN2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070225395-A1 Thermally stable cationic photocurable compositions WOLF JEAN-PIERRE 2007-09-27 US claimed
US-20050165141-A1 Thermally stable cationic photocurable compositions CIBA SPECIALTY CHEMICALS CORP. 2005-07-28 US claimed
EP-2076563-B1 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS BASF SE (DE) 2016-08-17 EP disclosed
US-8084522-B2 Thermally stable cationic photocurable compositions BASF SE (DE) 2011-12-27 US disclosed
US-20100304284-A1 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS IGM GROUP B.V. (NL) 2010-12-02 US disclosed
EP-2076563-A1 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS Ciba Holding Inc. (CH) 2009-07-08 EP disclosed
WO-2008049743-A1 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS CIBA HOLDING INC. (CH) 2008-05-02 WO disclosed
US-20070225395-A1 Thermally stable cationic photocurable compositions WOLF JEAN-PIERRE 2007-09-27 US disclosed
EP-1709099-A2 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS Ciba Specialty Chemicals Holding Inc. (CH) 2006-10-11 EP disclosed
WO-2005070989-A2 THERMALLY STABLE CATIONIC PHOTOCURABLE COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-08-04 WO disclosed
US-20050165141-A1 Thermally stable cationic photocurable compositions CIBA SPECIALTY CHEMICALS CORP. 2005-07-28 US disclosed
US-20010036591-A1 Iodonium salts as latent acid donors IGM GROUP B.V. (NL) 2001-11-01 US disclosed
US-6306555-B1 RADIATION-SENSITIVE COMPOSITION COMPRISING CATIONICALLY OR ACID-CATALYTICALLY POLYMERISABLE OR CROSSLINKABLE COMPOUND OR COMPOUND THAT INCREASES ITS SOLUBILITY IN DEVELOPER UNDER ACTION OF ACID, AND AT LEAST ONE DIARYLIODONIUM SALT CIBA SPECIALTY CHEMICALS CORP. 2001-10-23 US disclosed