Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790563 | 0.85 | TRPA1 (0.43) | L3MBTL1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL29277321 | 0.83 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1CSNK2A3IDO1 | |
| SCHEMBL8658043 | 0.80 | DHFR (0.42) | L3MBTL1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13179975 | 0.79 | L3MBTL1 (0.39) | L3MBTL1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL5847395 | 0.79 | CSNK2A1 (0.57) | L3MBTL1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL5847393 | 0.79 | L3MBTL1 (0.39) | L3MBTL1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL21668224 | 0.76 | NPSR1 (0.38) | L3MBTL1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL44646 | 0.76 | BACE1 (0.62) | CSNK2A2CSNK2BCSNK2A1CSNK2A3HTR2A | |
| SCHEMBL93982 | 0.75 | IDO1 (0.58) | IDO1SLC6A4TSHRLMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL44146 | 0.75 | BACE1 (0.61) | CSNK2A2CSNK2BCSNK2A1CSNK2A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658239-A | Use of N-(4-tert-butylbenzyl)-3-chloro-N-[2-(4-chloro-3-ethyl-phenyl)-ethyl]-2-fluoro- 5-trifluoromethyl-benzamide for the treatment of eye diseases | 豪夫迈·罗氏有限公司 | 2016-06-08 | — | — | CN | disclosed |
| US-8426631-B2 | Fungicidal compounds, method for the production thereof, and use thereof to combat damaging fungi, and agents comprising the same | BASF SE (DE) | 2013-04-23 | — | — | US | disclosed |
| US-20100304966-A1 | Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same | BASF SE (DE) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100304966-A1 | Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same | CYP51A1, ERG28, CAT | L3MBTL1 1100/4885CSNK2A2 3803/4885CSNK2B 3692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.