Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406211 | 0.82 | DRD2 (0.46) | PLAUDRD2DRD3ADRA1AADRA2A | |
| SCHEMBL10558927 | 0.82 | DRD2 (0.46) | PLAUDRD2DRD3ADRA1AADRA2A | |
| Hydrochloric Acid SCHEMBL26650353 | 0.81 | DRD2 (0.44) | PLAUDRD2DRD3ADRA1AADRA2A | |
| SCHEMBL841205 | 0.78 | PLAU (0.55) | PLAUDRD2DRD3ADRA1AOPRK1 | |
| SCHEMBL22061859 | 0.78 | DRD2 (0.74) | PLAUDRD2DRD3ADRA1AAADAT | |
| SCHEMBL23045122 | 0.78 | TRPV1 (0.45) | ADRA1AADRA2ACYP2D6ADRA2BADRA2C | |
| SCHEMBL16233586 | 0.78 | ADRA2A (0.49) | ADRA1AADRA2ACYP2D6ADRA2BADRA2C | |
| SCHEMBL14591309 | 0.78 | PLAU (0.55) | PLAUDRD2DRD3ADRA1AAADAT | |
| SCHEMBL23045121 | 0.78 | TRPV1 (0.45) | ADRA1AADRA2ACYP2D6ADRA2BADRA2C | |
| SCHEMBL266906 | 0.78 | DRD2 (0.74) | PLAUDRD2DRD3ADRA1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298138-A1 | Aminoazoline and Urea Derivatives for Combating Animal Pests | BASF SE (DE) | 2010-11-25 | — | — | US | disclosed |
| EP-2120576-A2 | AMINOAZOLINE AND UREA DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008145615-A2 | AMINOAZOLINE AND UREA DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-12-04 | — | — | WO | disclosed |
| US-5389687-A | Selective antagonists of serotonin | ELI LILLY AND COMPANY (US) | 1995-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298138-A1 | Aminoazoline and Urea Derivatives for Combating Animal Pests | AADAT, INMT, SLC14A1 | PLAU 2238/4885DRD2 2130/4885DRD3 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.