Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ligustilide SCHEMBL28151404 | 0.81 | TRPA1 (1.00) | TRPA1 | |
| Ligustilide SCHEMBL11967666 | 0.81 | TRPA1 (1.00) | TRPA1 | |
| Ligustilide SCHEMBL4087027 | 0.81 | TRPA1 (1.00) | TRPA1 | |
| SCHEMBL11967655 | 0.75 | TRPA1 (0.61) | TRPA1 | |
| Ligustilide SCHEMBL27599046 | 0.73 | TRPA1 (0.81) | TRPA1 | |
| SCHEMBL1872402 | 0.70 | TRPA1 (0.54) | TRPA1 | |
| SCHEMBL11967654 | 0.67 | TRPA1 (0.51) | TRPA1 | |
| SCHEMBL15470520 | 0.64 | ALDH1A1 (0.66) | TRPA1POLBMAPTRAB9A | |
| SCHEMBL28015146 | 0.64 | ALDH1A1 (0.66) | TRPA1POLBMAPTRAB9A | |
| SCHEMBL15160718 | 0.58 | TRPA1 (0.40) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298427-A1 | Anti-inflammatory compositions and their use | DSM IP ASSETS B.V. (NL) | 2010-11-25 | — | — | US | disclosed |
| US-20090176873-A1 | NOVEL USE OF ORGANIC COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176873-A1 | NOVEL USE OF ORGANIC COMPOUNDS | F12, F13B, COL1A1 | TRPA1 309/4885POLB 2666/4885MAPT 4338/4885 |
| US-20100298427-A1 | Anti-inflammatory compositions and their use | COL1A1, COL2A1, F12 | TRPA1 729/4885POLB 2953/4885MAPT 4260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.