Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015146 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| SCHEMBL15470519 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| SCHEMBL17572144 | 0.85 | ALDH1A1 (0.65) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| SCHEMBL30234042 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| SCHEMBL17211775 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| SCHEMBL31751764 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| SCHEMBL317445 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| SCHEMBL873948 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| SCHEMBL901183 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPK1TRPA1KDM4E | |
| Z-Butylidenephthalide SCHEMBL290483 | 0.76 | TRPA1 (1.00) | ALDH1A1TSHRMAPK1TRPA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11013716-B2 | Method for providing an increased expression of telomerase, brain-derived neurotrophic factor, stromal cell-derived factor-1, CXC chemokine receptor 4, and/or immune regulatory factor of stem cell | HAWKING BIOLOGICAL TECHNOLOGY CO., LTD. (TW) | 2021-05-25 | — | — | US | disclosed |
| US-20160324826-A1 | METHOD FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | HAWKING BIOLOGICAL TECHNOLOGY CO., LTD. (TW) | 2016-11-10 | — | — | US | disclosed |
| US-20160324826-A1 | METHOD FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | HAWKING BIOLOGICAL TECHNOLOGY CO., LTD. (TW) | 2016-11-10 | — | — | US | disclosed |
| US-20140271568-A1 | METHOD AND KIT FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | Hawking Biological Technology Co., Ltd (TW) | 2014-09-18 | — | — | US | disclosed |
| US-20140271568-A1 | METHOD AND KIT FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | Hawking Biological Technology Co., Ltd (TW) | 2014-09-18 | — | — | US | disclosed |
| US-8729026-B2 | Method for inhibiting autophagy of motor neurons | CHINA MEDICAL UNIVERSITY (TW) | 2014-05-20 | — | — | US | disclosed |
| US-8729026-B2 | Method for inhibiting autophagy of motor neurons | CHINA MEDICAL UNIVERSITY (TW) | 2014-05-20 | — | — | US | disclosed |
| US-20140045765-A1 | METHOD FOR INHIBITING AUTOPHAGY OF MOTOR NEURONS | CHINA MEDICAL UNIVERSITY (TW) | 2014-02-13 | — | — | US | disclosed |
| US-20140045765-A1 | METHOD FOR INHIBITING AUTOPHAGY OF MOTOR NEURONS | CHINA MEDICAL UNIVERSITY (TW) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11013716-B2 | Method for providing an increased expression of telomerase, brain-derived neurotrophic factor, stromal cell-derived factor-1, CXC chemokine receptor 4, and/or immune regulatory factor of stem cell | CXCL12, CXCR4, BDNF | ALDH1A1 347/4885TSHR 920/4885MAPK1 1755/4885 |
| US-20140271568-A1 | METHOD AND KIT FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | CXCL12, CXCR4, BDNF | ALDH1A1 444/4885TSHR 931/4885MAPK1 877/4885 |
| US-20160324826-A1 | METHOD FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL | CXCL12, CXCR4, BDNF | ALDH1A1 347/4885TSHR 920/4885MAPK1 1755/4885 |
| US-20140045765-A1 | METHOD FOR INHIBITING AUTOPHAGY OF MOTOR NEURONS | ATG7, BECN1, SQSTM1 | ALDH1A1 1312/4885TSHR 4595/4885MAPK1 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.