Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440463 | 0.79 | FKBP1A (0.39) | MAPTKDM4EFKBP1AALDH1A1GAA | |
| SCHEMBL13604536 | 0.76 | MAPT (0.37) | MAPTKDM4EFKBP1AALDH1A1GAA | |
| SCHEMBL11007149 | 0.74 | MAPT (0.39) | MAPTFKBP1AALDH1A1GAALMNA | |
| SCHEMBL10473457 | 0.73 | MEN1 (0.43) | MAPTKDM4EFKBP1AALDH1A1GAA | |
| SCHEMBL8436953 | 0.73 | MEN1 (0.43) | MAPTKDM4EFKBP1AALDH1A1GAA | |
| SCHEMBL8436951 | 0.73 | MEN1 (0.43) | MAPTKDM4EFKBP1AALDH1A1GAA | |
| SCHEMBL13611696 | 0.73 | MEN1 (0.43) | MAPTKDM4EFKBP1AALDH1A1GAA | |
| SCHEMBL10473454 | 0.73 | MEN1 (0.43) | MAPTKDM4EFKBP1AALDH1A1GAA | |
| SCHEMBL464766 | 0.70 | KMT2A (0.37) | MAPTFKBP1AALDH1A1LMNAKMT2A | |
| SCHEMBL20113215 | 0.70 | KMT2A (0.37) | MAPTFKBP1AALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592610-B2 | Spiroheterocyclic tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-26 | — | — | US | disclosed |
| US-20130012384-A1 | Spiroheterocyclic Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-01-10 | — | — | US | disclosed |
| US-8318956-B2 | Spiroheterocyclic tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | DDT, PTPRG, WIZ | MAPT 4229/4885KDM4E 4133/4885FKBP1A 1100/4885 |
| US-20130012384-A1 | Spiroheterocyclic Tetronic Acid Derivatives | DDT, PTPRG, WIZ | MAPT 4229/4885KDM4E 4133/4885FKBP1A 1100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.