Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611696 | 0.85 | MEN1 (0.43) | FKBP1AGAAALDH1A1CYP3A4MAPT | |
| SCHEMBL10473454 | 0.85 | MEN1 (0.43) | FKBP1AGAAALDH1A1CYP3A4MAPT | |
| SCHEMBL8436951 | 0.85 | MEN1 (0.43) | FKBP1AGAAALDH1A1CYP3A4MAPT | |
| SCHEMBL10473457 | 0.85 | MEN1 (0.43) | FKBP1AGAAALDH1A1CYP3A4MAPT | |
| SCHEMBL8436953 | 0.85 | MEN1 (0.43) | FKBP1AGAAALDH1A1CYP3A4MAPT | |
| SCHEMBL8438674 | 0.83 | FKBP1A (0.38) | FKBP1AGAAALDH1A1CYP3A4MAPT | |
| SCHEMBL3305700 | 0.80 | CYP3A4 (0.44) | FKBP1AALDH1A1CYP3A4MAPTTSHR | |
| SCHEMBL3762837 | 0.79 | MAPT (0.39) | FKBP1AGAAALDH1A1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL4117447 | 0.79 | RAB9A (0.46) | GAAALDH1A1THRBATML3MBTL1 | |
| SCHEMBL3391192 | 0.78 | CYP3A4 (0.42) | FKBP1AALDH1A1CYP3A4MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880138-A | ANTAGONISTS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 1999-03-09 | — | — | US | disclosed |