Sugi Predict

Sugi Predict / Compounds / SCHEMBL376340

SCHEMBL376340

SCHEMBL376340

NC(=O)c1ccc(S(=O)(=O)NC(=O)c2ccccc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.73
▸ LMNA P02545 1/20 0.73
▸ KMT2A Q03164 1/20 0.73
▸ FLT1 P17948 3/20 0.69
▸ FLT4 P35916 3/20 0.69
▸ KDR P35968 3/20 0.69
▸ L3MBTL1 Q9Y468 2/20 0.69
▸ BCL2L1 Q07817 3/20 0.58
▸ MCL1 Q07820 3/20 0.58
▸ P4HTM Q9NXG6 3/20 0.55
▸ PTGS2 P35354 2/20 0.55
▸ CA1 P00915 1/20 0.55
▸ CA2 P00918 1/20 0.55
▸ CA9 Q16790 1/20 0.55
▸ MAOA P21397 1/20 0.54
▸ PTGS1 P23219 1/20 0.54
▸ POLB P06746 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ PARP1 P09874 1/20 0.53
▸ MAPT P10636 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12489988 0.95 MEN1 (0.66) MEN1LMNAKMT2AFLT1FLT4
SCHEMBL25424924 0.92 BCL2L1 (0.70) MEN1LMNAKMT2AFLT1FLT4
SCHEMBL8424044 0.86 FLT1 (0.73) MEN1LMNAKMT2AFLT1FLT4
SCHEMBL5931288 0.86 FLT1 (0.71) MEN1LMNAKMT2AFLT1FLT4
SCHEMBL174010 0.86 FLT1 (0.77) MEN1LMNAKMT2AFLT1FLT4
Sulfabenzamide SCHEMBL93841 0.85 KMT2A (1.00) MEN1LMNAKMT2AFLT1FLT4
SCHEMBL39499 0.84 KDM4E (0.55) MEN1LMNAKMT2AFLT1FLT4
SCHEMBL29011132 0.84 FLT1 (0.74) MEN1LMNAKMT2AFLT1FLT4
Potassium SCHEMBL30358590 0.84 FLT1 (0.74) MEN1LMNAKMT2AFLT1FLT4
SCHEMBL6161386 0.84 MEN1 (0.60) MEN1LMNAKMT2AFLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110072853-A The benz triazolinone of weeding 巴斯夫欧洲公司 2019-07-30 — — CN claimed
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines BASF SE (DE) 2019-07-02 — — US claimed
US-20170367340-A1 Herbicidal Isoxazolo[5,4-B]pyridines BASF SE (DE) 2017-12-28 — — US claimed
US-20160037777-A1 Herbicidal Isoxazolo[5,4-B]pyridines BASF SE (DE) 2016-02-11 — — US claimed
CN-105028414-A HERBICIDE-SAFENER COMBINATION BAYER IP GMBH 2015-11-11 — — CN claimed
EP-2939541-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 — — EP claimed
CN-102300459-A Herbicide-safener combination — 2011-12-28 — — CN claimed
WO-2011138280-A2 HERBICIDE/SAFENER COMBINATIONS COMPRISING ARYLPYRIDAZINONES AND SAFENER BAYER CROPSCIENCE AG (DE) 2011-11-10 — — WO claimed
CN-102227162-A Herbicide-safener combination BAYER CROPSCIENCE AG 2011-10-26 — — CN claimed
CN-102223795-A Herbicide-safener combination BAYER CROPSCIENCE AG 2011-10-19 — — CN claimed
EP-2369927-A2 HERBICIDE-SAFENER COMBINATION Bayer CropScience AG (DE) 2011-10-05 — — EP claimed
EP-2369929-A2 HERBICIDE-SAFENER COMBINATION Bayer CropScience AG (DE) 2011-10-05 — — EP claimed
EP-2210492-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-07-28 — — EP claimed
WO-2010060581-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 — — WO claimed
US-20100137136-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 — — US claimed
WO-2010060579-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 — — WO claimed
US-20100137138-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 — — US claimed
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 — — US claimed
EP-2191716-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 — — EP claimed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137138-A1 HERBICIDE/SAFENER COMBINATION DDT, GSTO1, GAP43 MEN1 4051/4885LMNA 3655/4885KMT2A 2182/4885
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 MEN1 4689/4885LMNA 4429/4885KMT2A 2661/4885
US-20100137136-A1 HERBICIDE/SAFENER COMBINATION DDT, GAP43, CYP2W1 MEN1 3652/4885LMNA 3660/4885KMT2A 1948/4885
US-20160037777-A1 Herbicidal Isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 MEN1 4689/4885LMNA 4429/4885KMT2A 2661/4885
US-20100137137-A1 HERBICIDE/SAFENER COMBINATION DDT, CYP2W1, GAP43 MEN1 3489/4885LMNA 4155/4885KMT2A 1867/4885
US-20170367340-A1 Herbicidal Isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 MEN1 4689/4885LMNA 4429/4885KMT2A 2661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.