Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093763 | 0.93 | RAB9A (0.55) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2092460 | 0.87 | SMN1; SMN2 (0.50) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL15000704 | 0.83 | SMN1; SMN2 (0.48) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2093864 | 0.82 | ALDH1A1 (0.44) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2093742 | 0.81 | EPHX2 (0.51) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL13001609 | 0.81 | RORC (0.46) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2094358 | 0.79 | POLB (0.51) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2091593 | 0.79 | MEN1 (0.52) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2095265 | 0.78 | NPC1 (0.44) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL3764117 | 0.78 | ACSS2 (0.49) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311787-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2010-12-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311787-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | CXCR2, CXCL8, CCR9 | MAPT 1416/4885RAB9A 1725/4885SMN1; SMN2 4722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.