Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.48 |
| ▸ | RAB9A | P51151 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5548005 | 0.79 | NPC1 (0.57) | NPC1RAB9AKMT2AMEN1NTRK1 | |
| SCHEMBL30554088 | 0.78 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1NTRK1 | |
| SCHEMBL25382759 | 0.78 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1NTRK1 | |
| SCHEMBL14697393 | 0.76 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1NTRK1 | |
| SCHEMBL2030050 | 0.75 | MAPK14 (0.38) | NPC1RAB9AKMT2AMEN1NTRK1 | |
| SCHEMBL22341606 | 0.75 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1NTRK1 | |
| SCHEMBL15880590 | 0.74 | MAPT (0.51) | NPC1RAB9AKMT2AMEN1NTRK1 | |
| SCHEMBL8863163 | 0.74 | LDHA (0.57) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25854530 | 0.74 | NPC1 (0.55) | NPC1RAB9AKMT2AMEN1NTRK1 | |
| SCHEMBL411193 | 0.73 | RAB9A (0.57) | NPC1RAB9AKMT2AMEN1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312226-A1 | Amide Compound | FAAH, FAAH2, CNR2 | NPC1 1078/4885RAB9A 1416/4885KMT2A 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.